Bhattarai Rachana, Carabin Hélène, Flores-Rivera Jose, Corona Teresa, Proaño Jefferson V, Flisser Ana, Budke Christine M
Department of Veterinary Integrative Biosciences, Texas A&M University College of Veterinary Medicine & Biomedical Sciences, College Station, Texas, United States.
Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City,, Oklahoma, United States.
Rev Inst Med Trop Sao Paulo. 2018;60:e20. doi: 10.1590/s1678-9946201860020. Epub 2018 May 28.
The objective of this study was to estimate the direct costs associated with the diagnosis and treatment of neurocysticercosis (NCC) during pre-hospitalization, hospitalization, and post-hospitalization periods for 108 NCC patients treated at the Instituto Nacional de Neurologia y Neurocirugia (INNN) in Mexico City, Mexico. Information on clinical manifestations, diagnostic tests, hospitalizations, surgical procedures, prescription medication, and other treatments was collected via medical chart reviews. Uncertain values for costs and frequency of treatments were imputed using bootstrap techniques. The average per-patient pre-hospitalization and hospitalization costs were US$ 257 (95% CI: 185 - 329) and US$ 2,576 (95% CI: 2,244 - 2,908), respectively. Post-hospitalization costs tended to decrease over time, with estimates for the first five years post-hospitalization of US$ 475 (95% CI: 423 - 527), US$ 228 (95% CI: 167 - 288), US$ 157 (95% CI: 111 - 202), US$ 150 (95% CI: 106 - 204), and US$ 91 (95% CI: 27 - 154), respectively. NCC results in a significant economic burden for patients requiring hospitalization, with this burden continuing years post-hospitalization.
本研究的目的是估算墨西哥城墨西哥国立神经病学与神经外科研究所(INNN)治疗的108例神经囊尾蚴病(NCC)患者在院前、住院和出院后期间与NCC诊断和治疗相关的直接费用。通过查阅病历收集有关临床表现、诊断检查、住院情况、外科手术、处方药和其他治疗的信息。使用自助法技术估算费用和治疗频率的不确定值。每位患者的院前平均费用和住院平均费用分别为257美元(95%CI:185 - 329)和2576美元(95%CI:2244 - 2908)。出院后费用随时间推移呈下降趋势,出院后前五年的估算费用分别为475美元(95%CI:423 - 527)、228美元(95%CI:167 - 288)、157美元(95%CI:111 - 202)、150美元(95%CI:106 - 204)和91美元(95%CI:27 - 154)。NCC给需要住院治疗的患者带来了巨大的经济负担,且这种负担在出院后数年仍持续存在。