Barrena Benjamin G, Phillips Billy J, Moran Kenneth J, Betz Sasha J
Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134, USA.
Indian Health Service Hospital, PO Box 600, Tuba City, AZ, 86045, USA.
Head Neck Pathol. 2019 Jun;13(2):247-250. doi: 10.1007/s12105-018-0933-3. Epub 2018 May 30.
Ameloblastomas are benign but aggressive odontogenic tumors that most commonly affect the posterior mandible. Approximately 15% occur in the maxilla, with a subset thought to originate from the epithelial lining of the sinonasal cavities. Histologically, sinonasal ameloblastomas are identical to those of the oral cavity, with classical features of palisaded columnar basilar cells surrounding a central proliferation that resembles the stellate reticulum of a developing tooth. Unlike the gnathic variant, sinonasal ameloblastomas tend to affect males more than females, and the incidence of diagnosis peaks at a later age, approximately 60 years old. The overall prognosis is favorable, with local recurrence being the most common long-term sequalae.
成釉细胞瘤是良性但具有侵袭性的牙源性肿瘤，最常累及下颌骨后部。约15%发生在上颌骨，其中一部分被认为起源于鼻窦腔的上皮衬里。组织学上，鼻窦成釉细胞瘤与口腔成釉细胞瘤相同，具有典型特征，即栅栏状柱状基底细胞围绕着类似于发育中牙齿星网状层的中央增殖区。与颌骨型不同，鼻窦成釉细胞瘤往往男性比女性更易受累，诊断发病率高峰在较晚年龄，约60岁。总体预后良好，局部复发是最常见的长期后遗症。
