Weintraub Z, Iancu T C, Sheinfeld M, Gonda M, Kraiem Z
Biol Neonate. 1985;47(3):186-8. doi: 10.1159/000242112.
Adenosine 3',5'-monophosphate (cAMP) was measured in matched samples of maternal plasma (MV) and umbilical artery (UA) and vein (UV) of 14 normal infants born following an uncomplicated vaginal delivery. There was good correlation between UA and UV cAMP levels, which seems to indicate that the fetoplacental unit maintains a constant equilibrium of the nucleotide concentration in the umbilical circulation. There was a markedly increased UA cAMP concentration at term relative to that of MV, as well as an arteriovenous gradient of plasma cAMP level (UA greater than UV) in the fetoplacental circulation, which strongly suggest that the high cAMP levels in the cord blood originate mainly from the fetus.
在14例顺产的正常婴儿的配对样本中，测量了母体血浆（MV）、脐动脉（UA）和脐静脉（UV）中的3',5'-环磷酸腺苷（cAMP）。UA和UV中的cAMP水平具有良好的相关性，这似乎表明胎儿-胎盘单位在脐循环中维持核苷酸浓度的恒定平衡。足月时，相对于MV，UA中的cAMP浓度显著升高，并且在胎儿-胎盘循环中存在血浆cAMP水平的动静脉梯度（UA大于UV），这强烈表明脐血中的高cAMP水平主要源于胎儿。
