Division of Hospital Medicine, Children's Hospital Los Angeles.
Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles.
J Pediatr Gastroenterol Nutr. 2018 Aug;67(2):e30-e35. doi: 10.1097/MPG.0000000000002033.
The objective of the study was to identify factors associated with length of stay (LOS) and 30-day hospital revisit for patients hospitalized with acute pancreatitis (AP).
Multicenter, retrospective cohort study using the Pediatric Health Information System database. Multilevel linear and logistic regression was used to identify factors independently associated with the primary outcome variables of LOS and 30-day hospital revisit in children aged 1 and 18 years discharged with a primary discharge diagnosis of AP from participating hospitals between 2008 and 2013.
For the 7693 discharges, median LOS was 4 days (interquartile range 3-7 days) and 30-day revisit rate 17.6% (n = 1356). Discharges were primarily girls (55%), Caucasian (46%), and 6 years old or older (85%). On multilevel regression, factors independently associated with both longer LOS and higher revisit odds included malignant and gastrointestinal complex chronic conditions (CCCs) and total parenteral nutrition use while hospitalized. Male gender was associated with both lower LOS (adjusted length of stay = -0.6 days, 95% confidence interval [CI] = -0.8 to -0.4) and decreased revisit odds (aOR 0.85; 95% CI = 0.74 to 0.97). Hispanic ethnicity was associated with increased LOS (adjusted length of stay = +0.8 days, 95% CI = +0.5 to +1.1), but no change in revisit odds.
Certain demographic and clinical factors, including gender, ethnicity, and type of CCC, were independently associated with LOS and risk of 30-day hospital revisit for pediatric AP. Children with malignant and gastrointestinal CCCs who require total parenteral nutrition are at highest risk for both longer LOS and hospital revisit when admitted with AP. These patient populations may benefit from intensive care coordination when hospitalized for AP.
本研究旨在确定与急性胰腺炎(AP)住院患者的住院时间(LOS)和 30 天内医院复诊相关的因素。
使用儿科健康信息系统数据库进行多中心回顾性队列研究。使用多级线性和逻辑回归来确定与 LOS 和 30 天内医院复诊的主要结局变量相关的因素,这些变量在 2008 年至 2013 年期间,从参与医院以急性胰腺炎为主要出院诊断出院的 1 岁和 18 岁的儿童中筛选。
在 7693 例出院患者中,中位 LOS 为 4 天(四分位距 3-7 天),30 天复诊率为 17.6%(n=1356)。出院患者主要为女孩(55%)、白种人(46%)和 6 岁或以上(85%)。在多水平回归中,与 LOS 延长和复诊几率升高均相关的因素包括恶性和胃肠道复杂慢性病(CCC)以及住院期间使用全胃肠外营养。男性与 LOS 降低相关(调整后的 LOS=-0.6 天,95%置信区间[CI]为-0.8 至-0.4),复诊几率降低(aOR 0.85;95%CI 为 0.74 至 0.97)。西班牙裔与 LOS 延长相关(调整后的 LOS=+0.8 天,95%CI 为+0.5 至+1.1),但复诊几率无变化。
某些人口统计学和临床因素,包括性别、种族和 CCC 类型,与儿科 AP 的 LOS 和 30 天内医院复诊风险独立相关。患有恶性和胃肠道 CCC 且需要全胃肠外营养的儿童在因 AP 入院时,LOS 和医院复诊的风险最高。这些患者群体在因 AP 住院时可能受益于重症监护协调。