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移植后他克莫司诱发的糖尿病酮症酸中毒:文献综述

Posttransplant Tacrolimus-Induced Diabetic Ketoacidosis: Review of the Literature.

作者信息

Ammari Zaid, Pak Stella C, Ruzieh Mohammed, Dasa Osama, Tiwari Abhinav, Jaume Juan C, Alfonso-Jaume Maria A

机构信息

Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, USA.

Division of Endocrinology, Diabetes and Metabolism, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, USA.

出版信息

Case Rep Endocrinol. 2018 May 9;2018:4606491. doi: 10.1155/2018/4606491. eCollection 2018.

DOI:10.1155/2018/4606491
PMID:29854487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5966672/
Abstract

Diabetic ketoacidosis (DKA) in patients receiving tacrolimus as part of their immunosuppressive regimen is a rarely reported adverse event. We report a patient with autosomal dominant polycystic kidney disease (ADPKD) and no known history of diabetes mellitus who presented with DKA, 3 months after kidney transplantation.

摘要

接受他克莫司作为免疫抑制方案一部分的患者发生糖尿病酮症酸中毒(DKA)是一种鲜有报道的不良事件。我们报告一例常染色体显性多囊肾病(ADPKD)患者,既往无糖尿病史,肾移植3个月后出现DKA。

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Medicine (Baltimore). 2019 Sep;98(36):e16992. doi: 10.1097/MD.0000000000016992.

本文引用的文献

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Tacrolimus confers lower acute rejection rates and better renal allograft survival compared to cyclosporine.与环孢素相比,他克莫司可降低急性排斥反应发生率,并提高肾移植存活率。
World J Transplant. 2016 Dec 24;6(4):697-702. doi: 10.5500/wjt.v6.i4.697.
2
A rare but important adverse effect of tacrolimus in a heart transplant recipient: diabetic ketoacidosis.
Turk J Pediatr. 2015 Sep-Oct;57(5):533-5.
3
Tacrolimus-Induced Diabetic Ketoacidosis After Allogeneic Bone Marrow Transplant.异基因骨髓移植后他克莫司诱发的糖尿病酮症酸中毒
Exp Clin Transplant. 2017 Dec;15(6):702-703. doi: 10.6002/ect.2015.0047. Epub 2015 Dec 1.
4
Clinical evolution of post-transplant diabetes mellitus.移植后糖尿病的临床演变
Nephrol Dial Transplant. 2016 Mar;31(3):495-505. doi: 10.1093/ndt/gfv368. Epub 2015 Nov 3.
5
Hypomagnesemia and the Risk of New-Onset Diabetes Mellitus after Kidney Transplantation.低镁血症与肾移植后新发糖尿病的风险
J Am Soc Nephrol. 2016 Jun;27(6):1793-800. doi: 10.1681/ASN.2015040391. Epub 2015 Oct 8.
6
Tacrolimus-Induced Diabetic Ketoacidosis and Effect of Switching to Everolimus: A Case Report.他克莫司诱发的糖尿病酮症酸中毒及转换为依维莫司的效果:一例报告
Transplant Proc. 2015 Jun;47(5):1528-30. doi: 10.1016/j.transproceed.2015.04.075.
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Tacrolimus in pancreas transplant: a focus on toxicity, diabetogenic effect and drug-drug interactions.他克莫司在胰腺移植中的应用:聚焦毒性、致糖尿病作用及药物相互作用
Expert Opin Drug Metab Toxicol. 2014 Nov;10(11):1585-605. doi: 10.1517/17425255.2014.964205. Epub 2014 Sep 26.
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Diabetic ketoacidosis associated with acute pancreatitis in a heart transplant recipient treated with tacrolimus.一名接受他克莫司治疗的心脏移植受者发生糖尿病酮症酸中毒合并急性胰腺炎。
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