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阴道血管肌纤维母细胞瘤作为阴道肿物脱垂的罕见病因:一例报告及文献复习

A Vaginal Angiomyofibroblastoma as a Rare Cause of a Prolapsing Vaginal Mass: A Case Report and Review of the Literature.

作者信息

Calvert Harriet, Kapurubandara Supuni, Nikam Yogesh, Sharma Raghwa, Achan Anita

机构信息

Department of Obstetrics and Gynaecology, The Maitland Hospital, Maitland, NSW, Australia.

Department of Obstetrics and Gynaecology, John Hunter Hospital, Newcastle, NSW, Australia.

出版信息

Case Rep Obstet Gynecol. 2018 Apr 29;2018:8579026. doi: 10.1155/2018/8579026. eCollection 2018.

DOI:10.1155/2018/8579026
PMID:29854515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5949183/
Abstract

INTRODUCTION

Angiomyofibroblastoma (AMFB) is a rare, benign, mesenchymal cell tumour which presents as a slow-growing mass. It is most commonly seen in the vulva and is often mistaken for Bartholin's abscess. It is histologically diagnosed by the presence of stromal cells intermingled with small blood vessels. It is morphologically similar to cellular angiofibroma and aggressive angiomyxoma, the latter of which is locally invasive and has a possibility of metastasis and a high risk of local recurrence. There is one reported case of an AMFB undergoing sarcomatous transformation.

CASE REPORT

We report a case of a multiparous, 36-year-old woman with an anterior vaginal mass which was inappropriately treated as a vaginal prolapse prior to definitive surgical management. This is only the second reported case of an AMFB presenting as a prolapsing mass.

摘要

引言

血管肌成纤维细胞瘤(AMFB)是一种罕见的良性间充质细胞瘤,表现为生长缓慢的肿块。它最常见于外阴,常被误诊为巴氏腺脓肿。其组织学诊断依据是存在与小血管混杂的基质细胞。它在形态上与细胞性血管纤维瘤和侵袭性血管黏液瘤相似,后者具有局部侵袭性,有转移的可能性且局部复发风险高。有一例血管肌成纤维细胞瘤发生肉瘤样变的报道。

病例报告

我们报告一例36岁经产妇,其阴道前壁有一肿块,在明确手术治疗前被不恰当地当作阴道脱垂处理。这是第二例报道的以脱垂肿块形式出现的血管肌成纤维细胞瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/671eb90ea1eb/CRIOG2018-8579026.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/ba44e064fe44/CRIOG2018-8579026.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/a6715fc45f19/CRIOG2018-8579026.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/d125f2ba0c4c/CRIOG2018-8579026.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/671eb90ea1eb/CRIOG2018-8579026.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/ba44e064fe44/CRIOG2018-8579026.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/2d5c37a8ea4d/CRIOG2018-8579026.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/9e57d3c6757b/CRIOG2018-8579026.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/310566bd6845/CRIOG2018-8579026.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/b186390db74b/CRIOG2018-8579026.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/a6715fc45f19/CRIOG2018-8579026.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/d125f2ba0c4c/CRIOG2018-8579026.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e3c/5949183/671eb90ea1eb/CRIOG2018-8579026.008.jpg

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本文引用的文献

1
Local recurrent vaginal aggressive angiomyxoma misdiagnosed as cellular angiomyofibroblastoma: A case report.局部复发性阴道侵袭性血管黏液瘤误诊为细胞性血管肌纤维母细胞瘤:一例报告。
Exp Ther Med. 2016 May;11(5):1893-1895. doi: 10.3892/etm.2016.3097. Epub 2016 Feb 19.
2
Ultrasound plays a key role in imaging and management of genital angiomyofibroblastoma: a case report.超声在生殖器血管肌纤维母细胞瘤的成像和管理中发挥关键作用:一例报告
J Med Case Rep. 2015 Oct 28;9:248. doi: 10.1186/s13256-015-0715-4.
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Vulvovaginal angiomyofibroblastomas: morphologic, immunohistochemical, and fluorescence in situ hybridization analysis for deletion of 13q14 region.
外阴阴道血管平滑肌脂肪瘤:13q14 缺失的形态学、免疫组织化学和荧光原位杂交分析。
Hum Pathol. 2014 Aug;45(8):1647-55. doi: 10.1016/j.humpath.2014.03.020. Epub 2014 Apr 18.
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Angiomyofibroblastoma of the vulva.外阴血管肌纤维母细胞瘤
Obstet Gynecol Sci. 2013 Sep;56(5):349-51. doi: 10.5468/ogs.2013.56.5.349. Epub 2013 Sep 14.
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Transvaginal sonographic features of perineal masses in the female lower urogenital tract: a retrospective study of 71 patients.女性下泌尿生殖道会阴肿物的经阴道超声特征:71例患者的回顾性研究
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Angiomyofibroblastoma of the vulva: a case report of a pedunculated variant and review of the literature.外阴血管肌纤维母细胞瘤:一例带蒂型病例报告及文献复习。
J Low Genit Tract Dis. 2012 Apr;16(2):149-54. doi: 10.1097/LGT.0b013e318231217b.
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Aggressive angiomyxoma.侵袭性血管黏液瘤。
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Large paravaginal angiomyofibroblastoma: magnetic resonance imaging findings.巨大阴道旁血管肌纤维母细胞瘤:磁共振成像表现。
Jpn J Radiol. 2011 Feb;29(2):152-5. doi: 10.1007/s11604-010-0512-3. Epub 2011 Feb 27.
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Huge pedunculated angiomyofibroblastoma of the vulva.巨大外阴带蒂血管肌纤维母细胞瘤。
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