Cipolla Calogero, Florena Ada Maria, Ferrara Gabriella, Di Gregorio Riccardo, Unti Elettra, Giannone Antonino G, Lazzaro Luigi A, Graceffa Giuseppa, Pantuso Gianni
Department of Surgical, Oncological and Oral Sciences, Division of General and Oncological Surgery, University of Palermo, Palermo, Italy.
Department of Sciences for Promotion of Health and Mother and Child Care, Anatomic Pathology, University of Palermo, Palermo, Italy.
Case Rep Surg. 2018 May 8;2018:7020538. doi: 10.1155/2018/7020538. eCollection 2018.
Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown etiopathogenesis and with definite features of imaging, histopathology, and immunohistochemistry. It was first described by Martel et al. in 2004, and to date, only 151 cases have been reported.
We report a case of SANT of the spleen detected in a 66-year-old Caucasian, without comorbidities, presented to our department with epigastric pain. We, also, presented a review of the literature.
SANT is a benign incidentally vascular condition in the majority of cases. The wide age and gender distribution in our review is in accordance with that in previous studies in English literature. In our opinion, splenectomy is the choice treatment because it is at the same time diagnostic and therapeutic in a definitive way.
脾脏硬化性血管瘤样结节性转化（SANT）是一种罕见的良性血管病变，其病因发病机制不明，具有明确的影像学、组织病理学和免疫组化特征。它于2004年由马特尔等人首次描述，迄今为止，仅报告了151例病例。
我们报告了一例在一名66岁无合并症的白种人中发现的脾脏SANT病例，该患者因上腹部疼痛前来我院就诊。我们还对文献进行了综述。
在大多数情况下，SANT是一种良性的偶然发生的血管疾病。我们综述中的广泛年龄和性别分布与之前英文文献中的研究一致。我们认为，脾切除术是首选治疗方法，因为它同时具有明确的诊断和治疗作用。
