Sohail Amir Humza, Eze Anthony, Sohail Sachal, Hadi Yousaf Bashir, Haider Zishan, Maurer James
Department of Surgery, NYU Langone Health Long Island, New York, USA.
Harvard T. H. Chan School of Public Health, Harvard University, Cambridge, Massachusetts, USA.
J Surg Case Rep. 2021 Sep 15;2021(9):rjab323. doi: 10.1093/jscr/rjab323. eCollection 2021 Sep.
Sclerosing angiomatoid nodular transformation (SANT) of the spleen is a rare benign vascular lesion with unknown pathogenesis and no definitive pathognomonic radiological features. The majority of patients with SANT are asymptomatic, and the lesion is an incidental finding on cross-sectional imaging performed for unrelated reasons or during intra-abdominal surgery. However, in the symptomatic minority, abdominal pain is the most commonly reported symptom. SANT generally remains stable or has very slow growth, making it amenable to surveillance using serial cross-sectional imaging. Herein, we report the unusual case of SANT in a 30-year-old female with rapid growth from 6.0 × 5.6 × 4.4 cm to 8.0 × 6.6 × 7.2 cm over 21 months. Given the rapid growth, it was imperative to rule out malignancy. Thus, the patient underwent a laparoscopic total splenectomy. For SANT, splenectomy serves the dual purpose of diagnosis and definitive therapy.
脾脏硬化性血管瘤样结节性转化（SANT）是一种罕见的良性血管病变，其发病机制不明，也没有明确的特征性影像学表现。大多数SANT患者无症状，该病变是在因其他无关原因进行的横断面成像检查中或腹部手术期间偶然发现的。然而，在少数有症状的患者中，腹痛是最常报告的症状。SANT通常保持稳定或生长非常缓慢，这使得通过系列横断面成像进行监测成为可能。在此，我们报告一例不寻常的SANT病例，一名30岁女性，在21个月内病变从6.0×5.6×4.4厘米迅速生长至8.0×6.6×7.2厘米。鉴于其快速生长，排除恶性肿瘤势在必行。因此，该患者接受了腹腔镜全脾切除术。对于SANT，脾切除术兼具诊断和确定性治疗的双重目的。
