Samlowski W E, Abbott T M, Kepas D E, Eyre H J
Gynecol Oncol. 1985 May;21(1):111-7. doi: 10.1016/0090-8258(85)90241-0.
A case of metastatic placental-site trophoblastic tumor (trophoblastic pseudotumor) is presented and compared to four previously reported cases. Chemotherapy with MAC (methotrexate, dactinomycin, cyclophosphamide), aggressive surgical debulking, and radiotherapy were ineffective in producing disease regression. Only two of the four similar cases in the literature showed short responses (4-7 months) to several different aggressive multiagent chemotherapy regimens. Optimal therapeutic outcome is likely to result from an early diagnosis and aggressive surgical treatment of localized tumor.
本文报告了一例转移性胎盘部位滋养细胞肿瘤（滋养细胞假瘤），并与之前报道的四例病例进行了比较。采用MAC（甲氨蝶呤、放线菌素D、环磷酰胺）化疗、积极的手术减瘤及放疗均未能使疾病缓解。文献中四例类似病例中，只有两例对几种不同的积极联合化疗方案有短期反应（4 - 7个月）。早期诊断并积极手术治疗局限性肿瘤可能会取得最佳治疗效果。
