Li Zhe, Maitz Peter
1Burns Unit, Concord Hospital, Concord, New South Wales 2139 Australia.
Skin Laboratory, NSW Statewide Burns Service, Concord, New South Wales Australia.
Burns Trauma. 2018 May 28;6:13. doi: 10.1186/s41038-018-0117-0. eCollection 2018.
Cell therapy has emerged as an important component of life-saving procedures in treating burns. Over past decades, advances in stem cells and regenerative medicine have offered exciting opportunities of developing cell-based alternatives and demonstrated the potential and feasibility of various stem cells for burn wound healing. However, there are still scientific and technical issues that should be resolved to facilitate the full potential of the cellular devices. More evidence from large, randomly controlled trials is also needed to understand the clinical impact of cell therapy in burns. This article aims to provide an up-to-date review of the research development and clinical applications of cell therapies in burn wound healing and skin regeneration.
细胞疗法已成为治疗烧伤的救命程序的重要组成部分。在过去几十年中，干细胞和再生医学的进展为开发基于细胞的替代疗法提供了令人兴奋的机会，并证明了各种干细胞在烧伤创面愈合中的潜力和可行性。然而，仍有一些科学和技术问题需要解决，以充分发挥细胞治疗设备的潜力。还需要更多来自大型随机对照试验的证据，以了解细胞疗法对烧伤的临床影响。本文旨在对细胞疗法在烧伤创面愈合和皮肤再生中的研究进展及临床应用进行最新综述。
