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Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study.遗传性 DNA 修复突变前列腺癌患者的临床结局：国际研究的回顾性分析。
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Intraductal/ductal histology and lymphovascular invasion are associated with germline DNA-repair gene mutations in prostate cancer.导管内/导管组织学及淋巴管浸润与前列腺癌种系DNA修复基因突变相关。
Prostate. 2018 Apr;78(5):401-407. doi: 10.1002/pros.23484. Epub 2018 Jan 25.
3
Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair-deficient Prostate Cancer.胚系 DNA 修复缺陷型前列腺癌的治疗结局和杂合性丢失
Eur Urol. 2017 Jul;72(1):34-42. doi: 10.1016/j.eururo.2017.02.023. Epub 2017 Mar 1.
4
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.转移性前列腺癌男性患者的遗传性DNA修复基因突变
N Engl J Med. 2016 Aug 4;375(5):443-53. doi: 10.1056/NEJMoa1603144. Epub 2016 Jul 6.
5
DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.转移性前列腺癌中的DNA修复缺陷与奥拉帕利
N Engl J Med. 2015 Oct 29;373(18):1697-708. doi: 10.1056/NEJMoa1506859.
6
Integrative clinical genomics of advanced prostate cancer.晚期前列腺癌的整合临床基因组学
Cell. 2015 May 21;161(5):1215-1228. doi: 10.1016/j.cell.2015.05.001.

Germline genetic testing in prostate cancer - further enrichment in variant histologies?

作者信息

Markowski Mark C, Antonarakis Emmanuel S

机构信息

Departments of Oncology and Urology, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD 21287, USA.

出版信息

Oncoscience. 2018 Apr 29;5(3-4):62-64. doi: 10.18632/oncoscience.403. eCollection 2018 Mar.

DOI:10.18632/oncoscience.403
PMID:29854870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5978447/
Abstract
摘要