Gao Jiayi, Li Xingyue, Zheng Yuanyuan, Qin Qian, Chen Di
Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases of Henan Province, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
College of Medical Laboratory, Dalian Medical University, Dalian 116044, China.
Foods. 2024 May 30;13(11):1714. doi: 10.3390/foods13111714.
Polycyclic aromatic hydrocarbons are considered to be potentially genotoxic and carcinogenic to humans. For non-smoking populations, food is the main source of polycyclic aromatic hydrocarbons exposure. Due to their lipophilic nature, oils and fats rank among the food items with the highest polycyclic aromatic hydrocarbon content. Consequently, the detection of polycyclic aromatic hydrocarbons in edible oils is critical for the promotion of human health. This paper reviews sample pretreatment methods, such as liquid-phase-based extraction methods, adsorbent-based extraction methods, and the QuEChERS (quick, easy, cheap, effective, rugged, and safe) method, combined with detection techniques like mass spectrometry and chromatography-based techniques for accurate quantification of polycyclic aromatic hydrocarbons in edible oils since 2010. An overview on the advances of the methods discussed herein, along with a commentary addition of current challenges and prospects, will guide researchers to focus on developing more effective detection methods and control measures to reduce the potential risks and hazards posed by polycyclic aromatic hydrocarbons.
多环芳烃被认为对人类具有潜在的遗传毒性和致癌性。对于非吸烟人群而言，食物是多环芳烃暴露的主要来源。由于其亲脂性，油脂是多环芳烃含量最高的食品之一。因此，检测食用油中的多环芳烃对促进人类健康至关重要。本文综述了自2010年以来用于食用油中多环芳烃准确定量的样品预处理方法，如基于液相的萃取方法、基于吸附剂的萃取方法和QuEChERS（快速、简便、廉价、有效、耐用和安全）方法，以及与质谱和基于色谱的技术等检测技术相结合的方法。本文对所讨论方法的进展进行了概述，并对当前的挑战和前景进行了评论补充，这将引导研究人员专注于开发更有效的检测方法和控制措施，以降低多环芳烃带来的潜在风险和危害。
