College of Physics, Jilin Normal University, Siping 136000, China.
Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China.
Molecules. 2018 Jun 1;23(6):1330. doi: 10.3390/molecules23061330.
Many studies have shown that it is important to consider the harmful effects of phenolic hormones on the human body. Traditional UV detection has many limitations, so there is a need to develop new detection methods. We demonstrated a simple and rapid surface-enhanced resonance Raman scattering (SERRS) based detection method of trace amounts of phenolic estrogen. As a result of the coupling reaction, there is the formation of strong SERRS activity of azo compound. Therefore, the detection limits are as low as 0.2 × 10 for estrone (E1), estriol (E3), and bisphenol A (BPA). This method is universal because each SERRS fingerprint of the azo dyes a specific hormone. The use of this method is applicable for the testing of phenolic hormones through coupling reactions, and the investigation of other phenolic molecules. Therefore, this new method can be used for efficient detection.
许多研究表明，考虑酚类激素对人体的有害影响很重要。传统的紫外检测有许多局限性，因此需要开发新的检测方法。我们展示了一种简单快速的基于表面增强共振拉曼散射（SERRS）的痕量酚类雌激素检测方法。由于偶联反应的发生，偶氮化合物具有很强的 SERRS 活性。因此，检测限低至 0.2×10-8mol/L 对于雌酮（E1）、雌三醇（E3）和双酚 A（BPA）。由于每种偶氮染料的 SERRS 指纹都代表一种特定的激素，因此该方法具有通用性。通过偶联反应，该方法可用于检测酚类激素，并可用于研究其他酚类分子。因此，这种新方法可以用于高效检测。
