Douchet C, Gelard M, Ahingora N, Anoh K, Choho A
Med Trop (Mars). 1985 Jan-Mar;45(1):59-66.
From 1981 to 1983, 1998 vaginal samples have been microbiologically examined in Abidjan. The average age was 23. Pathogen agents take often the place of normal lactobacillus flora. The presence of most of the microbian germs (Enterobacteriaceae, Neisseriae, Trichomonas, Corynehactery) was not increased by the pregnant state. But yeast and Candida albicans in particular, were found significantly more frequent in pregnant women. Candida albicans, serotype B, was, by far, the most frequently discovered. It has offered a real resistance against 5 fluorocytosin, as it can be observed in Europe. In vitro, ketoconazole appeared less efficient than econazole. On the contrary, nystatin and amphotericin B presented a great and constant activity against all yeasts of Candida genus.
1981年至1983年期间，在阿比让对1998份阴道样本进行了微生物学检查。平均年龄为23岁。病原体常常取代正常的乳酸杆菌菌群。大多数微生物（肠杆菌科、奈瑟菌属、滴虫、棒状杆菌）的存在在怀孕状态下并未增加。但尤其是酵母菌和白色念珠菌，在孕妇中发现的频率明显更高。到目前为止，最常发现的是B型白色念珠菌。正如在欧洲所观察到的那样，它对5-氟胞嘧啶具有真正的抗性。在体外，酮康唑的效果似乎不如益康唑。相反，制霉菌素和两性霉素B对念珠菌属的所有酵母菌都表现出强大且持续的活性。
