Child Neuropsychiatry Unit, Medicine & Surgery Department, University of Parma, Italy.
Child Neuropsychiatry Unit, Medicine & Surgery Department, University of Parma, Italy.
Eur J Paediatr Neurol. 2018 Sep;22(5):757-762. doi: 10.1016/j.ejpn.2018.05.009. Epub 2018 May 24.
Nowadays, no general consensus was achieved regarding neonatal status epilepticus and its definition. Indeed, different criteria (mainly based on seizure duration) were used. Whereas a recent proposal has been developed to define status epilepticus in older ages, it seems that the peculiar characteristics of neonatal seizures and of the immature brain make difficult to find a tailored definition for this period of life. Achieving a consensus on this entity would mean to make the first step toward a targeted therapeutic strategy of intervention.
目前,对于新生儿癫痫持续状态及其定义尚未达成共识。实际上,不同的标准(主要基于发作持续时间)被用于定义新生儿癫痫持续状态。尽管最近提出了一种定义老年人癫痫持续状态的建议,但新生儿癫痫发作和未成熟大脑的特殊特征使得为这一生命阶段找到一个合适的定义变得困难。就这一实体达成共识意味着朝着有针对性的治疗干预策略迈出了第一步。