Department of Community Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore 575001, India.
Kasturba Medical College, Manipal Academy of Higher Education, Mangalore 575001, India.
Biomed Res Int. 2018 May 15;2018:1759125. doi: 10.1155/2018/1759125. eCollection 2018.
Leptospirosis is a major neglected public health problem and is highly underreported in India. The spectrum of clinical features ranges from subclinical infection to multiorgan failure. The burden of leptospirosis is more in developing countries.
The present study was designed to assess the sociodemographic characteristics, clinical feature, and outcome of leptospirosis patients.
This record based retrospective study was conducted in hospitals affiliated to Kasturba Medical College, Mangalore. The registries of the leptospirosis patients during the period of four years between January 2011 and December 2014 were reviewed and the information on demographic and clinical profile of the leptospirosis patients was recorded in the data capture sheet. The information obtained was analyzed using SPSS version 11.5.
The study included 202 leptospirosis victims. The mean age of the study population was 40.48 (±14.8) years. Majority of the patients presented with fever (92.1%) at the time of admission. Acute renal failure was found to be the most common complication (79.2%). Case fatality rate was found to be 3.5%.
High proportion of cases indirectly reflects the endemic nature of the disease in the study setting. The clinical presentation of the leptospirosis is highly protean and may vary from a mild illness to life-threatening complications as evident from the current study.
钩端螺旋体病是一个主要的被忽视的公共卫生问题，在印度的报告率极低。其临床特征范围从亚临床感染到多器官衰竭。钩端螺旋体病的负担在发展中国家更为严重。
本研究旨在评估钩端螺旋体病患者的社会人口统计学特征、临床特征和结局。
这是一项基于病历的回顾性研究，在 Mangalore 的 Kasturba 医学院附属医院进行。对 2011 年 1 月至 2014 年 12 月期间四年内的钩端螺旋体病患者的病历进行了回顾，并将钩端螺旋体病患者的人口统计学和临床特征信息记录在数据采集表中。使用 SPSS 版本 11.5 对获得的信息进行分析。
该研究包括 202 例钩端螺旋体病患者。研究人群的平均年龄为 40.48（±14.8）岁。大多数患者在入院时出现发热（92.1%）。急性肾衰竭是最常见的并发症（79.2%）。病死率为 3.5%。
高比例的病例间接反映了研究环境中疾病的地方性。从目前的研究可以看出，钩端螺旋体病的临床表现非常多样，可能从轻度疾病到危及生命的并发症不等。
