Access Sensor Technologies LLC, 430 N College Ave, Fort Collins, CO 80524, USA.
Analyst. 2018 Jun 25;143(13):3085-3090. doi: 10.1039/c8an00632f.
Here we report a new microfluidic paper-based analytical device (mPAD) for quantifying metals in water. Metals represent an important class of water contaminants that come from a variety of sources including mining, transportation, manufacturing, waste management, and energy production. Current technologies for quantifying aquatic metals in water are expensive, relatively slow, tedious, provide inadequate performance, and are difficult to use in a field setting. As a result, a need exists for simple, portable, power-free measurement tools that enable rapid in-field quantification of aquatic metals. The reported metal test cards, referred to as the On-Target Water Chemistry test cards, represent a major improvement over previously reported linear distance-based detection systems comprised of paper. With the On-Target approach, the sample flows outwards radially and reacts with colorimetric complexing agents, significantly reducing assay time. The diameter of the resulting color formation is directly proportional to analyte concentration. The On-Target cards were used for detecting copper, iron, and zinc with detection limits as low as 0.1 ppm in ∼3 min and single ppb in combination with a membrane pre-concentration system.
我们在此报告了一种新的用于定量水中金属的微流控纸基分析装置（mPAD）。金属是一类重要的水中污染物，其来源包括采矿、运输、制造、废物管理和能源生产等多种途径。目前用于定量水中金属的技术昂贵、相对较慢、繁琐、性能不足，并且难以在现场使用。因此，需要简单、便携、无需电源的测量工具，以便能够快速现场定量水中金属。所报道的金属测试卡，称为 On-Target Water Chemistry 测试卡，相对于以前报道的基于线性距离的纸基检测系统有了重大改进。使用 On-Target 方法，样品向外呈放射状流动并与比色络合剂反应，显著缩短了测定时间。所得显色直径与分析物浓度成正比。On-Target 卡用于检测铜、铁和锌，检测限低至 0.1ppm（约 3 分钟），与膜预浓缩系统结合时可达到单个 ppb。
