Bendicho Carlos, Lavilla Isela, Pena-Pereira Francisco, de la Calle Inmaculada, Romero Vanesa
Department of Analytical and Food Chemistry, Faculty of Chemistry, University of Vigo, Campus As Lagoas-Marcosende s/n, 36310 Vigo, Spain.
Sensors (Basel). 2021 Jan 16;21(2):604. doi: 10.3390/s21020604.
The development of disposable sensors that can be easily adapted to every analytical problem is currently a hot topic that is revolutionizing many areas of science and technology. The need for decentralized analytical measurements at real time is increasing for solving problems in areas such as environment pollution, medical diagnostic, food quality assurance, etc., requiring fast action. Despite some current limitations of these devices, such as insufficient detection capability at (ultra)trace level and risk of interferent effects due to matrix, they allow low-cost analysis, portability, low sample consumption, and fast response. In the last years, development of paper-based analytical devices has undergone a dramatic increase for on-site detection of toxic metal ions and other pollutants. Along with the great availability of cellulose substrates, the immobilization of receptors providing enhanced recognition ability, such as a variety of nanomaterials, has driven the design of novel sensing approaches. This review is aimed at describing and discussing the different possibilities arisen with the use of different nanoreceptors (e.g., plasmonic nanoparticles, quantum dots, carbon-based fluorescent nanoparticles, etc.) immobilized onto cellulose-based substrates for trace element detection, their advantages and shortcomings.
开发能够轻松适应各种分析问题的一次性传感器，是当前一个热门话题，正在彻底改变许多科技领域。为解决环境污染、医学诊断、食品质量保证等领域中需要快速行动的问题，对实时分散式分析测量的需求日益增加。尽管这些设备目前存在一些局限性，例如在（超）痕量水平下检测能力不足以及基质产生干扰效应的风险，但它们具有低成本分析、便携性、低样品消耗和快速响应的特点。近年来，用于现场检测有毒金属离子和其他污染物的纸质分析设备的开发急剧增加。随着纤维素底物的大量可得，诸如各种纳米材料等具有增强识别能力的受体的固定化，推动了新型传感方法的设计。本综述旨在描述和讨论将不同的纳米受体（例如等离子体纳米颗粒、量子点、碳基荧光纳米颗粒等）固定在纤维素基底物上用于痕量元素检测所产生的不同可能性、它们的优点和缺点。
