Wang Jizhe, Yan Zhuangzhi, Wen Junling
School of Communication and Information Engineering, Shanghai University, Shanghai, 200444.
Shanghai Institute of Biomedical Engineering, Shanghai University, Shanghai, 200444.
Zhongguo Yi Liao Qi Xie Za Zhi. 2018 Jan 30;42(1):1-6. doi: 10.3969/j.issn.1671-7104.2018.01.001.
Getting volume change of hippocampus by segmenting on brain MRI is an important step in the diagnose of Alzheimer's disease and other brain disease. Three dimensional segmentation can make use of the correlation of image in gray and spatial position, so it has high accuracy. This paper proposes a novel three-dimensional lattice Boltzmann model combined with the surface evolution of deformable model and taking the prior information as an external force term to constrain the evolution of three dimensional surfaces. In order to solve the problem of high computational cost caused by 3D segmentation, the parallelization of the method is programmed on single GPU platform and dual GPU platform. Comparison experiments were set to test the accuracy of segmentation and computational efficiency between the novel LB method and another method by using 20 real AD patient's MRI from ADNI. In ensuring the accuracy of the segmentation, the time can be reduced to 12.76 s on single GPU platform, and 17.32 s on dual GPU platform, contrasting 132.43 s on CPU platform. It fully validates the characteristics of lattice Boltzmann method which can be highly parallelized.
通过对脑部磁共振成像(MRI)进行分割来获取海马体的体积变化,是诊断阿尔茨海默病和其他脑部疾病的重要步骤。三维分割可以利用图像在灰度和空间位置上的相关性,因此具有较高的准确性。本文提出了一种新颖的三维格子玻尔兹曼模型,该模型结合了可变形模型的表面演化,并将先验信息作为外力项来约束三维表面的演化。为了解决三维分割导致的高计算成本问题,该方法在单GPU平台和双GPU平台上进行了并行化编程。通过使用来自阿尔茨海默病神经成像计划(ADNI)的20例真实AD患者的MRI,设置了对比实验来测试新型LB方法与另一种方法之间的分割准确性和计算效率。在确保分割准确性的情况下,单GPU平台上的时间可减少到12.76秒,双GPU平台上为17.32秒,而CPU平台上为132.43秒。这充分验证了格子玻尔兹曼方法可高度并行化的特性。