与肌萎缩侧索硬化症的一段历程

A Journey with Amyotrophic Lateral Sclerosis.

作者信息

Jeffery Deborah, Fish Anne F

机构信息

Deborah Jeffery, DNP, RN, is Director of Advanced Illness Management, Palliative Services at the Visiting Nurse Association of Greater St. Louis. She also is Director of Nursing at the Convent of the Immaculate Heart retirement community in St. Louis, Missouri. Anne F. Fish, PhD, RN, is an associate professor at the College of Nursing at the University of Missouri in St. Louis, Missouri.

出版信息

J Christ Nurs. 2018 Jul/Sep;35(3):152-159. doi: 10.1097/CNJ.0000000000000502.

DOI:10.1097/CNJ.0000000000000502

PMID:29863511

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Motor neurons are affected in certain patterns, such as cervical, thoracic, lumbar, and bulbar (facial) regions. Although initial presentations can vary, eventually upper and lower motor neurons are lost in the two types of ALS: familial and sporadic. A case study highlighting the reality of living with bulbar ALS relays Sister A's journey from early to late ALS. Etiology, pathophysiology, diagnosis, treatment, and clinical care are discussed.

摘要

肌萎缩侧索硬化症（ALS）是一种致命的神经退行性疾病。运动神经元以特定模式受到影响，如颈部、胸部、腰部和延髓（面部）区域。尽管最初表现可能各不相同，但最终在家族性和散发性这两种ALS类型中，上下运动神经元都会丧失。一项突出延髓型ALS患者生活现状的病例研究讲述了A修女从早期到晚期ALS的历程。文中还讨论了病因、病理生理学、诊断、治疗及临床护理。