Department of Ophthalmology, Sapporo City General Hospital, Sapporo, Japan.
Retina. 2019 Aug;39(8):1470-1477. doi: 10.1097/IAE.0000000000002209.
To examine the influence of inverted internal limiting membrane (ILM) flap technique on the outer retinal layer structures after macular hole (MH) surgery.
We included 24 eyes of 24 patients who underwent vitrectomy for large MHs (≥400 µm) with successful MH closure and observed for at least 6 months. Fourteen eyes were treated with inverted ILM flap technique (inverted group) and 10 with conventional ILM peeling (ILMP group). We evaluated the postoperative recovery rate of the external limiting membrane and ellipsoid zone and the best-corrected visual acuity.
The postoperative recovery rates of the external limiting membrane and ellipsoid zone in the inverted group were lower than those in the ILMP group (21.4 vs. 70.0%, P = 0.024; 0 vs. 30.0, P = 0.059, respectively). The external limiting membrane recovery period in the inverted group was significantly longer than that in the ILMP group (11.0 ± 1.7 vs. 3.4 ± 2.8 months, P = 0.015). The best-corrected visual acuity change (letters) in the inverted group was significantly smaller than that in the ILMP group (9.0 vs. 22.5, P = 0.040).
The poorer anatomical and visual results associated with inverted ILM flap compared with ILM peeling suggest the limitation of the ILM flap technique to repair refractory MHs.
观察内界膜翻转瓣技术对孔源性黄斑裂孔(MH)术后外层视网膜结构的影响。
纳入 24 例 24 只眼,这些眼均接受了玻璃体切除术治疗大孔(≥400 µm)MH ,并获得了成功的 MH 闭合,且至少随访 6 个月。其中 14 只眼接受内界膜翻转瓣技术(翻转组)治疗,10 只眼接受常规内界膜剥除术(ILMP 组)治疗。我们评估了外节膜和椭圆体带的术后恢复率以及最佳矫正视力。
翻转组的外节膜和椭圆体带的术后恢复率低于 ILMP 组(21.4%比 70.0%,P=0.024;0 比 30.0%,P=0.059)。翻转组的外节膜恢复时间明显长于 ILMP 组(11.0±1.7 比 3.4±2.8 个月,P=0.015)。翻转组的最佳矫正视力变化(字母)明显小于 ILMP 组(9.0 比 22.5,P=0.040)。
与 ILMP 剥除术相比,内界膜翻转瓣技术在解剖学和视力方面的结果较差,提示该技术在治疗难治性 MH 方面存在局限性。