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独生子女家庭与心血管代谢危险因素有关联吗:Caspian-V研究

Is single-child family associated with cardio-metabolic risk factors: the CASPIAN-V study.

作者信息

Kelishadi Roya, Qorbani Mostafa, Rezaei Fatemeh, Motlagh Mohammad Esmaeil, Djalalinia Shirin, Ziaodini Hasan, Taheri Majzoubeh, Ochi Fatemeh, Shafiee Gita, Aminaei Tahereh, Mahdavi Gorabi Armita, Heshmat Ramin

机构信息

Pediatrics Department, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.

Non-Communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.

出版信息

BMC Cardiovasc Disord. 2018 Jun 4;18(1):109. doi: 10.1186/s12872-018-0844-y.

DOI:10.1186/s12872-018-0844-y
PMID:29866072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5987466/
Abstract

BACKGROUND

In the present study, the association of the cardio-metabolic risk factors and the status of single-child family were studied in a national representative sample of Iranian children and adolescents.

METHODS

This cross sectional study was conducted as the fifth round of "Childhood and Adolescence Surveillance and PreventIon of Adult Non- communicable disease" surveys. The students' questionnaire was derived from the World Health Organization-Global School Student Health Survey. Using survey data analysis methods, data from questionnaires'; anthropometric measures and biochemical information analyzed by logistic regression analysis.

RESULTS

Overall, 14,274 students completed the survey (participation rate: 99%); the participation rate for blood sampling from students was 91.5%. Although in univariate logistic regression model, single child students had an increased risk of abdominal obesity [OR: 1.37; 95% CI: 1.19-1.58)], high SBP [OR: 1.58; 95% CI:1.17-2.14)], high BP [OR: 1.21; 95% CI:1.01-1.45)] and generalized obesity [OR: 1.27; 95% CI:1.06-1.52)], in multiple logistic regression model, only association of single child family with abdominal obesity remained statistically significant [OR: 1.28; 95% CI:1.1-1.50)]. Also in multivariate logistic regression model, for each increase of a child in the family the risk of abdominal obesity [OR: 0.95; 95% CI: 0.91-0.97), high SBP [OR: 0.88; 95% CI: 0.81-0.95)] and generalized obesity [OR: 0.95; 95% CI: 0.91-0.99)] decreased significantly.

CONCLUSION

The findings of this study serve as confirmatory evidence on the association of cardio-metabolic risk factors with single-child family in children and adolescents. The findings of study could be used for better health planning and more complementary research.

摘要

背景

在本研究中,在一个具有全国代表性的伊朗儿童和青少年样本中,研究了心脏代谢危险因素与独生子女家庭状况之间的关联。

方法

本横断面研究作为“儿童和青少年成人非传染性疾病监测与预防”调查的第五轮进行。学生问卷源自世界卫生组织全球学校学生健康调查。使用调查数据分析方法,对问卷数据、人体测量指标和生化信息进行逻辑回归分析。

结果

总体而言,14274名学生完成了调查(参与率:99%);学生血液采样的参与率为91.5%。尽管在单变量逻辑回归模型中,独生子女学生腹部肥胖[比值比(OR):1.37;95%置信区间(CI):1.19 - 1.58]、高收缩压[OR:1.58;95% CI:1.17 - 2.14]、高血压[OR:1.21;95% CI:1.01 - 1.45]和全身性肥胖[OR:1.27;95% CI:1.06 - 1.52]的风险增加,但在多变量逻辑回归模型中,只有独生子女家庭与腹部肥胖的关联仍具有统计学意义[OR:1.

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