RIBP-EA 4707, SFR Condorcet FR CNRS 3417, University of Reims Champagne-Ardenne, Reims, 51100, France.
LBMI laboratory, Gembloux Agro-Bio Tech, SFR Condorcet FR CNRS 3417, University of Liège, Gembloux, B-5030, Belgium.
Sci Rep. 2018 Jun 4;8(1):8534. doi: 10.1038/s41598-018-26838-y.
Stimulation of plant innate immunity by natural and synthetic elicitors is a promising alternative to conventional pesticides for a more sustainable agriculture. Sugar-based bolaamphiphiles are known for their biocompatibility, biodegradability and low toxicity. In this work, we show that Synthetic Rhamnolipid Bolaforms (SRBs) that have been synthesized by green chemistry trigger Arabidopsis innate immunity. Using structure-function analysis, we demonstrate that SRBs, depending on the acyl chain length, differentially activate early and late immunity-related plant defense responses and provide local increase in resistance to plant pathogenic bacteria. Our biophysical data suggest that SRBs can interact with plant biomimetic plasma membrane and open the possibility of a lipid driven process for plant-triggered immunity by SRBs.
通过天然和合成诱导剂刺激植物先天免疫是一种有前途的替代传统农药的方法，可实现更可持续的农业。基于糖的两性离子表面活性剂以其生物相容性、可生物降解性和低毒性而闻名。在这项工作中，我们表明，通过绿色化学合成的合成鼠李糖脂双分子层（SRBs）可以触发拟南芥先天免疫。通过结构-功能分析，我们证明 SRBs 可以根据酰链长度的不同，差异化地激活早期和晚期与免疫相关的植物防御反应，并为植物提供局部抗性以抵抗植物病原菌。我们的生物物理数据表明，SRBs 可以与植物仿生质膜相互作用，并为 SRBs 引发的植物触发免疫提供了一个可能由脂质驱动的过程。
