Fernández-de-Las-Peñas César, Plaza-Manzano Gustavo
Department of Physical Therapy, Occupational Therapy, Rehabilitation & Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain.
Cátedra de Investigación y Docencia en Fisioterapia: Terapia Manual y Punción Seca, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain.
Pain Manag. 2018 May 1;8(3):209-216. doi: 10.2217/pmt-2017-0063. Epub 2018 Jun 5.
Carpal tunnel syndrome (CTS) is considered just a peripheral neuropathy of the upper extremity associated to the compression of the median nerve. There is evidence suggesting the presence of complex sensitization mechanisms in CTS. These processes are manifested by symptoms in extra-median regions and the presence of bilateral sensory and motor impairments. These sensory and motor changes are not associated to electrodiagnostic findings. The presence of sensitization mechanisms suggests that CTS should not be considered just as a peripheral neuropathy. The presence of altered nociceptive gain processing should be considered for therapeutic management of CTS by considering the application of therapeutic interventions that modulate nociceptive barrage into the CNS.
腕管综合征（CTS）被认为只是一种与正中神经受压相关的上肢周围神经病变。有证据表明CTS存在复杂的致敏机制。这些过程表现为正中神经以外区域的症状以及双侧感觉和运动障碍。这些感觉和运动变化与电诊断结果无关。致敏机制的存在表明CTS不应仅被视为一种周围神经病变。在对CTS进行治疗管理时，应考虑到伤害性增益处理的改变，可考虑应用能调节传入中枢神经系统的伤害性传入的治疗干预措施。
