论“旨在测量主动脉僵硬度的脉搏波速度方法的数值评估和比较”。
Comment on 'Numerical assessment and comparison of pulse wave velocity methods aiming at measuring aortic stiffness'.
机构信息
Department of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London, SE1 7EH, United Kingdom.
出版信息
Physiol Meas. 2018 Jul 6;39(7):078001. doi: 10.1088/1361-6579/aaca80.
OBJECTIVE
A recent numerical study investigated the potential utility of peripheral PWV measurements for assessing aortic stiffness by simulating pulse wave propagation through the arterial tree.
APPROACH
In this Comment we provide additional analysis of the simulations in which arterial compliances were changed.
MAIN RESULTS
The analysis indicates that relationships between aortic and peripheral pulse transit times (PTTs) may not be constant when compliances change.
SIGNIFICANCE
Peripheral PWV measurements may have greatest utility in particular clinical settings in which either an assumption can be made about possible changes in compliance, allowing aortic PTT to be estimated from peripheral PTT; or, one wishes to assess changes in peripheral PWV over time.
目的
最近的一项数值研究通过模拟脉搏波在动脉树中的传播，探讨了外周 PWV 测量在评估主动脉僵硬度方面的潜在应用。
方法
在本评论中，我们提供了对改变动脉顺应性的模拟的进一步分析。
主要结果
分析表明，当顺应性改变时，主动脉和外周脉搏传播时间（PTT）之间的关系可能不是恒定的。
意义
外周 PWV 测量在外周 PWV 随时间变化的特定临床环境中可能具有最大的应用价值，在这些环境中，要么可以假设顺应性可能发生变化，从而可以从外周 PTT 估计主动脉 PTT；要么，希望评估外周 PWV 的随时间变化。
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