Weng Y C, Gu D S, Zeng D Q, Zhang L
Department of Otolaryngology Head and Neck Surgery, Chinese People's Armed Police Force, Zhejiang Corps Hospital, Jiaxing, 314000, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Apr 5;30(7):542-545. doi: 10.13201/j.issn.1001-1781.2016.07.009.
To investigate the effectiveness and compliance of the 2 year specific immunotherapy in patients with allergic rhinitis. Two hundred and sixty-two patients of allergic rhinitis were treated with SLIT for 2 years. The symptom questionnaire about effectiveness and compliance were obtained 2 years after SLIT. The patient satisfaction was also investigated. Sixty patients had complete compliance and 202 patients had poor compliance. Of the 142 children, 40 (28%) cases had complete compliance, and of the 118 adult patients, 20 cases (17%) had complete compliance. There was obvious difference between the two (<0.05). Comparing of before and after treatment, total medication score, total nasal symptom score and every symptom score decreased obviously (<0.05). Two years after treatment, the total effective rate was 63%,there was significant difference between the children group and the adult group (<0.05). There are a lot of factors affecting the treatment compliance of sublingual immunotherapy, such as patients, family, health care workers and social support, etc. In the course of treatment, a series of strategies can be adopted to improve the treatment compliance. SLIT is an effective method for the treatment of allergic rhinitis, and the treatment effect of children is better.
探讨变应性鼻炎患者进行2年特异性免疫治疗的有效性及依从性。262例变应性鼻炎患者接受了2年的舌下特异性免疫治疗(SLIT)。在SLIT治疗2年后获取关于有效性及依从性的症状调查问卷。同时对患者满意度进行了调查。60例患者完全依从,202例患者依从性差。在142例儿童患者中,40例(28%)完全依从,在118例成年患者中,20例(17%)完全依从。两者之间存在显著差异(<0.05)。治疗前后比较,总用药评分、总鼻部症状评分及各项症状评分均明显降低(<0.05)。治疗2年后,总有效率为63%,儿童组与成年组之间存在显著差异(<0.05)。影响舌下免疫治疗依从性的因素众多,如患者、家庭、医护人员及社会支持等。在治疗过程中,可采取一系列策略来提高治疗依从性。SLIT是治疗变应性鼻炎的一种有效方法,且儿童的治疗效果更佳。