López-Villalobos José Antonio, Sacristán-Martín Ana María, Garrido-Redondo Mercedes, Martínez-Rivera María Teresa, López-Sánchez María Victoria, Rodríguez-Molinero Luis, Camina-Gutiérrez Ana Belén, Andrés-de Llano Jesús
Servicio de Psiquiatría, Complejo Asistencial de Universitario de Palencia, Palencia, España.
Servicio de Pediatra, Atención Primaria, Palencia, España.
An Pediatr (Engl Ed). 2019 May;90(5):272-279. doi: 10.1016/j.anpedi.2018.04.016. Epub 2018 Jun 2.
The health-related quality of life (HRQoL) questionnaire is important in order to assess the effects of therapeutic intervention. The aim of this study is to analyse HRQoL, comparing cases of attention deficit hyperactivity disorder (ADHD) treated with methylphenidate (ADHD-T), untreated cases (ADHD-N), and controls.
The study included a sample of 228 participants between 8 and 14 years old (114 controls, 57 ADHD-T, and 57 ADHD-N). Consecutive sampling was used in ADHD according to DSM-IV criteria (ADHD Rating Scales IV), and random sampling of controls matched by gender and age. The evaluation of HRQoL was made by using KIDSCREEN-52 parent version.
The intensity of ADHD symptoms is significantly lower in ADHD-T than in ADHD-N. There is a moderate significant correlation between greater intensity of ADHD symptoms and worse HRQoL. ADHD cases have significantly worse HRQoL than controls on psychic well-being, mood, relationship with parents and friends, school environment, and social acceptance. The cases of ADHD-T have significantly better HRQoL than ADHD-N in the school dimension, but do not differ significantly in other dimensions of KIDSCREEN-52.
It would be advisable that the treatment of ADHD integrates multi-dimensional therapeutic models that improve the basic symptoms of the disorder, as well as the HRQoL.
与健康相关的生活质量(HRQoL)问卷对于评估治疗干预效果十分重要。本研究旨在分析HRQoL,比较接受哌甲酯治疗的注意力缺陷多动障碍(ADHD)病例(ADHD-T)、未治疗病例(ADHD-N)和对照组。
该研究纳入了228名8至14岁的参与者样本(114名对照组、57名ADHD-T和57名ADHD-N)。根据《精神疾病诊断与统计手册》第四版标准(ADHD评定量表IV)对ADHD进行连续抽样,并对性别和年龄匹配的对照组进行随机抽样。使用KIDSCREEN-52家长版对HRQoL进行评估。
ADHD-T组的ADHD症状强度显著低于ADHD-N组。ADHD症状强度越高与HRQoL越差之间存在中度显著相关性。ADHD病例在心理健康、情绪、与父母及朋友的关系、学校环境和社会接纳方面的HRQoL显著低于对照组。ADHD-T组在学校维度的HRQoL显著优于ADHD-N组,但在KIDSCREEN-52的其他维度上无显著差异。
ADHD的治疗宜采用多维治疗模式,以改善该疾病的基本症状以及HRQoL。