Lopez-Villalobos J A, Garrido-Redondo M, Sacristan-Martin A M, Martinez-Rivera M T, Lopez-Sanchez M V, Andres-De Llano J M, Rodriguez-Molinero L, Camina-Gutierrez A B
Complejo Asistencial Universitario de Palencia, Palencia, Espana.
Rev Neurol. 2018 Sep 16;67(6):195-202.
Health-related quality of life perceived by children and teenagers is important to assess the effects of therapeutic intervention.
To analyze quality of life, comparing cases of attention deficit hyperactivity disorder (ADHD) treated with methylphenidate, untreated cases and controls.
Sampling of 228 participants between 8 and 14 years-old. Consecutive sampling in ADHD according to DSM-IV criteria (ADHD Rating Scales IV) and random sampling of matched controls by sex and age. Evaluation of quality of life using KIDSCREEN-52 (children version). ANOVA with Bonferroni correction was used.
There is a moderate significant correlation between greater intensity of ADHD symptoms and worse quality of life, except in the dimension of physical well-being. Cases of untreated ADHD have significantly worse quality of life than controls on psychic well-being, mood, autonomy school environment and social acceptance. Cases of treated ADHD present similar results, except in the school environment and psychological well-being. The cases of ADHD treated only differ significantly from ADHD not treated in having a better school environment.
The cases of ADHD present dimensions of KIDSCREEN-52 with worse quality of life than controls and the cases of ADHD treated with methylphenidate only differ significantly from those not treated in presenting better results in the school environment.
评估治疗干预效果时,儿童和青少年所感知的与健康相关的生活质量很重要。
分析生活质量,比较用哌甲酯治疗的注意力缺陷多动障碍(ADHD)病例、未治疗病例及对照组。
对228名8至14岁参与者进行抽样。根据DSM-IV标准(ADHD评定量表IV)对ADHD进行连续抽样,并按性别和年龄对匹配的对照组进行随机抽样。使用儿童生活质量量表52项版(儿童版)评估生活质量。采用经Bonferroni校正的方差分析。
除身体健康维度外,ADHD症状强度越高与生活质量越差之间存在中度显著相关性。未治疗的ADHD病例在心理健康、情绪、自主性、学校环境和社会接纳方面的生活质量显著低于对照组。接受治疗的ADHD病例结果相似,但在学校环境和心理健康方面除外。仅接受治疗的ADHD病例与未接受治疗的ADHD病例相比,仅在学校环境方面有显著差异,前者更好。
ADHD病例在儿童生活质量量表52项版各维度上的生活质量均低于对照组,且用哌甲酯治疗的ADHD病例与未治疗的病例相比,仅在学校环境方面结果更好,存在显著差异。