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郊区慢性阻塞性肺疾病(COPD)的患病率以及与生物质烟雾暴露相关的呼吸道症状

Prevalence of COPD and respiratory symptoms associated with biomass smoke exposure in a suburban area.

作者信息

Ramírez-Venegas Alejandra, Velázquez-Uncal Mónica, Pérez-Hernández Rosaura, Guzmán-Bouilloud Nicolás Eduardo, Falfán-Valencia Ramcés, Mayar-Maya María Eugenia, Aranda-Chávez Adrian, Sansores Raúl H

机构信息

Tobacco Smoking and COPD Research Department, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico.

Research Department of Tobacco Smoking, Centro de Investigacion de Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.

出版信息

Int J Chron Obstruct Pulmon Dis. 2018 May 25;13:1727-1734. doi: 10.2147/COPD.S156409. eCollection 2018.

Abstract

INTRODUCTION

Biomass smoke exposure (BSE) is a recognized cause of COPD particularly in rural areas. However, little research has been focused on BSE in suburban areas.

OBJECTIVE

The aim of this study was to determine the prevalence of COPD, respiratory symptoms (RS) and BSE in women living in a suburban area of Mexico City exposed to BSE.

METHODS

A cross-sectional epidemiological survey of a female population aged >35 years was performed using a multistage cluster sampling strategy. The participants completed questionnaires on RS and COPD risk factors. The COPD prevalence was based on the postbronchodilator forced expiratory volume in the first second (FEV)/forced vital capacity (FVC) ratio. Of the 1,333 women who completed the respiratory questionnaires, spirometry data were obtained from 1,190, and 969 of these were scored as A-C.

RESULTS

The prevalence of BSE was 47%, and the estimated prevalence of COPD was 2.5% for the total population (n=969) and 3.1% for those with BSE only. The spirometry and oximetry values were significantly lower in women with greater exposure levels. The prevalence of RS (cough, phlegm, wheezing and dyspnea) was significantly higher in the women with BSE compared to those without exposure. We concluded that the association of COPD with biomass exposure is not only a rural phenomenon but also may be observed in the suburban areas of the big cities.

摘要

引言

生物质烟雾暴露(BSE)是慢性阻塞性肺疾病(COPD)的一个公认病因,尤其是在农村地区。然而,针对郊区生物质烟雾暴露的研究较少。

目的

本研究旨在确定墨西哥城郊区暴露于生物质烟雾的女性中慢性阻塞性肺疾病(COPD)、呼吸道症状(RS)和生物质烟雾暴露(BSE)的患病率。

方法

采用多阶段整群抽样策略,对年龄大于35岁的女性人群进行横断面流行病学调查。参与者完成了关于呼吸道症状和慢性阻塞性肺疾病风险因素的问卷调查。慢性阻塞性肺疾病的患病率基于支气管扩张剂使用后第一秒用力呼气量(FEV)/用力肺活量(FVC)比值。在1333名完成呼吸问卷的女性中,1190人获得了肺功能测定数据,其中969人的评分等级为A - C。

结果

生物质烟雾暴露的患病率为47%,总体人群(n = 969)慢性阻塞性肺疾病的估计患病率为2.5%,仅暴露于生物质烟雾的人群中为3.1%。暴露水平较高的女性,其肺功能测定和血氧测定值显著较低。与未暴露的女性相比,暴露于生物质烟雾的女性呼吸道症状(咳嗽、咳痰、喘息和呼吸困难)的患病率显著更高。我们得出结论,慢性阻塞性肺疾病与生物质暴露的关联不仅是农村现象,在大城市的郊区也可能存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72d2/5973474/2720d7e0d15c/copd-13-1727Fig1.jpg

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