Department of Chemistry, Center for Supramolecular Chemistry and Catalysis, Shanghai University, 99 Shangda Road, Shanghai, 200444, P. R. China.
Chem Commun (Camb). 2018 Jun 14;54(49):6412-6415. doi: 10.1039/c8cc03475c.
An unusual cascade reaction of isocyanide and enynone using Yb/Ag cooperative catalysis as a key step has been disclosed. The present strategy enables the double isocyanide insertion and subsequent 5-endo-dig cyclization, thus providing a quick access to structurally complex pyrrole-fused heterocycles.
一种不寻常的异氰化物和烯酮的级联反应，使用 Yb/Ag 协同催化作为关键步骤，已经被揭示。本策略能够实现双异氰化物插入和随后的 5-endo-dig 环化，从而为具有复杂结构的吡咯稠合杂环提供了快速途径。
