Tesarz J, Gerhardt A, Eich W
Klinik für Allgemeine Innere Medizin und Psychosomatik, Universitätsklinik Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Deutschland.
Schmerz. 2018 Aug;32(4):243-249. doi: 10.1007/s00482-018-0301-y.
Adult pain perception is influenced substantially by interactions between mind, body, and social environment during early life. Early stress exposure and traumatic life events induce powerful psychophysical stress reactions that exert multiple neurofunctional processes. This has significant implications for pain perception and pain processing. As part of this review, the complex relationships between traumatic stress experiences and associated psychobiological mechanisms of chronic pain will be discussed. Based on selected studies, psychophysiological findings are presented and possible underlying mechanisms are discussed. The article concludes with a discussion of potential implications for treatment.
成人的疼痛感知在很大程度上受到生命早期心理、身体和社会环境之间相互作用的影响。早期应激暴露和创伤性生活事件会引发强烈的心理生理应激反应,这些反应会产生多种神经功能过程。这对疼痛感知和疼痛处理具有重要意义。作为本综述的一部分,将讨论创伤性应激经历与慢性疼痛相关心理生物学机制之间的复杂关系。基于选定的研究,呈现心理生理学研究结果并讨论可能的潜在机制。文章最后讨论了对治疗的潜在影响。