血小板-淋巴细胞比值与中性粒细胞-淋巴细胞比值联合检测在预测[疾病名称]存在及其相关并发症方面的作用。需注意，原文中“the presence of and its associated complications”部分缺失具体疾病名称，以上译文为补充完整后的示意翻译。

The role of the PLR-NLR combination in the prediction of the presence of and its associated complications.

作者信息

Kaplan Mustafa, Ates Ihsan, Yuksel Mahmut, Arikan Mehmet F, Aydog Gulden, Turhan Nesrin, Gökbulut Volkan, Kayacetin Ertugrul

机构信息

Department of Gastroenterology, Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

Department of Internal Medicine, Ankara Numune Training and Research Hospital, Ankara, Turkey.

出版信息

Saudi J Gastroenterol. 2018 Sep-Oct;24(5):294-300. doi: 10.4103/sjg.SJG_29_18.

DOI:10.4103/sjg.SJG_29_18

PMID:29873316

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6152001/

Abstract

BACKGROUND/AIM: The aim of this study was to investigate the role of the platelet-to-lymphocyte ratio (PLR)-neutrophil-to-lymphocyte ratio (NLR) combination, in the prediction of the presence of Helicobacter pylori (HP) and its associated complications in the gastrointestinal system.

PATIENTS AND METHODS

In all, 1289 patients who underwent esophagogastroduodenoscopy and biopsy for HP were included in the study.

RESULTS

The ratio of patients with moderate and severe chronic gastritis was higher in HP (+) group than HP (-) group. The ratio of patients with levels 1-3 atrophy and intestinal metaplasia was higher in HP (+) group. Compared with HP (-) group, HP (+) had higher PLR and NLR levels. The ratio of HP (+) patients was higher in high-risk group compared with low- and medium-risk groups. HP invasion stage, the intestinal metaplasia level, and the ratio of patients with atrophy level "3" were higher in high-risk group compared with low- and medium-risk groups. Regression analysis showed that the PLR-NLR combination was an independent risk factor for both HP presence and moderate and severe chronic gastritis.

CONCLUSION

We found the PLR-NLR combination to be a good predictor of HP presence and gastrointestinal complications associated with HP.

摘要

背景/目的：本研究旨在探讨血小板与淋巴细胞比值（PLR）-中性粒细胞与淋巴细胞比值（NLR）组合在预测幽门螺杆菌（HP）存在及其在胃肠道系统相关并发症方面的作用。

患者与方法

本研究共纳入1289例行食管胃十二指肠镜检查及HP活检的患者。

结果

HP（+）组中度和重度慢性胃炎患者比例高于HP（-）组。HP（+）组1-3级萎缩和肠化生患者比例更高。与HP（-）组相比，HP（+）组PLR和NLR水平更高。高危组HP（+）患者比例高于低危和中危组。与低危和中危组相比，高危组HP侵袭阶段、肠化生程度及萎缩程度“3”级患者比例更高。回归分析表明，PLR-NLR组合是HP存在及中度和重度慢性胃炎的独立危险因素。