疼痛的学习与忘却
Learning and Unlearning of Pain.
作者信息
Cordier Larissa, Diers Martin
机构信息
Department of Psychosomatic Medicine and Psychotherapy, LWL University Hospital, Ruhr University Bochum, 44791 Bochum, Germany.
出版信息
Biomedicines. 2018 Jun 5;6(2):67. doi: 10.3390/biomedicines6020067.
Abstract
This review provides an overview of learning mechanisms and memory aspects for the development of chronic pain. Pain can be influenced in important ways by an individual's personality, by family, and by the sociocultural environment in which they live. Therefore, learning mechanisms can explain why pain experience and pain behavior can increase or decrease. Linking pain with positive consequences or removing negative consequences can contribute significantly to the chronification of pain. We will provide an overview of treatment options that use the characteristics of extinction. Operant extinction training and cognitive behavioral approaches show promising results for the treatment of chronic pain.
摘要
本综述概述了慢性疼痛发展过程中的学习机制和记忆方面。疼痛会受到个体性格、家庭以及其所处社会文化环境的重要影响。因此，学习机制可以解释为什么疼痛体验和疼痛行为会增加或减少。将疼痛与积极后果联系起来或消除消极后果会显著促进疼痛的慢性化。我们将概述利用消退特征的治疗方案。操作性消退训练和认知行为方法在慢性疼痛治疗中显示出了有前景的结果。
相似文献
1
Learning and Unlearning of Pain.
Biomedicines. 2018 Jun 5;6(2):67. doi: 10.3390/biomedicines6020067.
2
Autophosphorylation of alphaCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction.
Learn Mem. 2008 Oct 30;15(11):837-43. doi: 10.1101/lm.1049608. Print 2008 Nov.
3
Renewal of extinguished behavior in pigeons (Columba livia) does not require memory consolidation of acquisition or extinction in a free-operant appetitive conditioning paradigm.
Behav Brain Res. 2019 Sep 16;370:111947. doi: 10.1016/j.bbr.2019.111947. Epub 2019 May 15.
4
[Operant and cognitive behavioural treatments in chronic pain].
Ther Umsch. 2011 Sep;68(9):507-11. doi: 10.1024/0040-5930/a000203.
5
The operant and the classical in conditioned orientation of Drosophila melanogaster at the flight simulator.
Learn Mem. 2000 Mar-Apr;7(2):104-15. doi: 10.1101/lm.7.2.104.
6
Cognitive-behavioral and operant-behavioral therapy for people with fibromyalgia.
Reumatismo. 2012 Sep 28;64(4):275-85. doi: 10.4081/reumatismo.2012.275.
7
A Dynamic Theory of Acquisition and Extinction in Operant Learning.
Neural Netw. 1997 Mar;10(2):201-229. doi: 10.1016/s0893-6080(96)00067-6.
8
Learning pain-related fear: neural mechanisms mediating rapid differential conditioning, extinction and reinstatement processes in human visceral pain.
Neurobiol Learn Mem. 2014 Dec;116:36-45. doi: 10.1016/j.nlm.2014.08.003. Epub 2014 Aug 13.
9
Occasion setting, inhibition, and the contextual control of extinction in Pavlovian and instrumental (operant) learning.
Behav Processes. 2017 Apr;137:64-72. doi: 10.1016/j.beproc.2016.10.003. Epub 2016 Oct 6.
10
Post-Learning Sleep Transiently Boosts Context Specific Operant Extinction Memory.
Front Behav Neurosci. 2017 Apr 26;11:74. doi: 10.3389/fnbeh.2017.00074. eCollection 2017.
引用本文的文献
1
User-Driven Development of a Digital Behavioral Intervention for Chronic Pain: Multimethod Multiphase Study.
JMIR Form Res. 2025 Jul 8;9:e74064. doi: 10.2196/74064.
2
Adaptation and validation of the Croatian version of the inventory of parent/caregiver responses to the children's pain experience (IRPEDNA).
BMC Psychol. 2025 Jul 1;13(1):657. doi: 10.1186/s40359-025-02976-7.
3
Long-term back pain recall in Generation XXI adolescents: the role of sensitivity and pain history.
Pain Rep. 2025 May 20;10(3):e1272. doi: 10.1097/PR9.0000000000001272. eCollection 2025 Jun.
4
No More Evasion: Redefining Conflict Behaviour in Human-Horse Interactions.
Animals (Basel). 2025 Jan 31;15(3):399. doi: 10.3390/ani15030399.
5
Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain.
Medicina (Kaunas). 2024 Feb 7;60(2):285. doi: 10.3390/medicina60020285.
6
Social network sites as learning environments and their implications for mental health.
Front Digit Health. 2022 Oct 10;4:939740. doi: 10.3389/fdgth.2022.939740. eCollection 2022.
7
Abnormal Large-Scale Neuronal Network in High Myopia.
Front Hum Neurosci. 2022 Apr 15;16:870350. doi: 10.3389/fnhum.2022.870350. eCollection 2022.
8
Development, evaluation and implementation of a digital behavioural health treatment for chronic pain: study protocol of the multiphase DAHLIA project.
BMJ Open. 2022 Apr 15;12(4):e059152. doi: 10.1136/bmjopen-2021-059152.
9
The Good, the Bad, and the Ugly-Chances, Challenges, and Clinical Implications of Avoidance Research in Psychosomatic Medicine.
Front Psychiatry. 2022 Feb 18;13:841734. doi: 10.3389/fpsyt.2022.841734. eCollection 2022.
10
Impaired pain-related threat and safety learning in patients with chronic back pain.
Pain. 2022 Aug 1;163(8):1560-1570. doi: 10.1097/j.pain.0000000000002544. Epub 2021 Nov 25.
本文引用的文献
1
Spousal criticism and hostility in response to pain: what is the alternative?
Pain. 2018 Jan;159(1):1-2. doi: 10.1097/j.pain.0000000000001045.
2
Couples coping with chronic pain: How do intercouple interactions relate to pain coping?
Scand J Pain. 2017 Jul;16:150-157. doi: 10.1016/j.sjpain.2017.05.010. Epub 2017 Jun 28.
3
Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia.
Clin J Pain. 2017 Mar;33(3):215-221. doi: 10.1097/AJP.0000000000000422.
4
The fear-avoidance model of pain.
Pain. 2016 Aug;157(8):1588-1589. doi: 10.1097/j.pain.0000000000000574.
5
Learning to predict and control harmful events: chronic pain and conditioning.
Pain. 2015 Apr;156 Suppl 1:S86-S93. doi: 10.1097/j.pain.0000000000000107.
6
Cognitive Behavioral Therapy increases pain-evoked activation of the prefrontal cortex in patients with fibromyalgia.
Pain. 2012 Jul;153(7):1495-1503. doi: 10.1016/j.pain.2012.04.010. Epub 2012 May 20.
7
Treatment-related changes in brain activation in patients with fibromyalgia syndrome.
Exp Brain Res. 2012 May;218(4):619-28. doi: 10.1007/s00221-012-3055-2. Epub 2012 Mar 17.
8
Non-pharmacological treatment of chronic widespread musculoskeletal pain.
Best Pract Res Clin Rheumatol. 2011 Apr;25(2):299-309. doi: 10.1016/j.berh.2011.01.005.
9
Central pain mechanisms in chronic pain states--maybe it is all in their head.
Best Pract Res Clin Rheumatol. 2011 Apr;25(2):141-54. doi: 10.1016/j.berh.2011.02.005.
10
Time-scheduled vs. pain-contingent opioid dosing in chronic opioid therapy.
Pain. 2011 Jun;152(6):1256-1262. doi: 10.1016/j.pain.2011.01.005. Epub 2011 Feb 5.
Zotero 插件