Matsumura K, Sawada K, Ishida I, Seki Y, Fukuma S, Kuwabara T, Maruyama T
Gan No Rinsho. 1985 Mar;31(3):240-5.
Ten patients with histologically and/or cytologically confirmed lung cancer were treated with cis-platinum (CDDP) infused into the bronchial artery (BAI). Radiological findings on chest X-rays taken two weeks after BAI were evaluated according to Takeuchi's criteria. The radiological results were judged to be quite effective in one case of squamous cell carcinoma, with more than 50% shrinkage of the tumor shadow, and to be effective in nine others, with more than 20% shrinkage. As for the histological effects, grade III in one case of squamous cell carcinoma and grade IIa in two cases of adenocarcinoma and one of large cell carcinoma were obtained by Shimosato's criteria. In conclusion, BAI with CDDP was sufficiently useful as a chemotherapeutic modality for lung cancer, especially squamous cell carcinoma, because higher local dosage of CDDP can be delivered without systemic toxicity.
十名经组织学和/或细胞学确诊为肺癌的患者接受了经支气管动脉灌注顺铂（CDDP）的治疗（支气管动脉灌注化疗，BAI）。根据竹内标准对支气管动脉灌注化疗两周后拍摄的胸部X光片的放射学表现进行评估。放射学结果显示，1例鳞状细胞癌疗效显著，肿瘤阴影缩小超过50%，另有9例有效，肿瘤阴影缩小超过20%。在组织学疗效方面，根据下里标准，1例鳞状细胞癌达到III级，2例腺癌和1例大细胞癌达到IIa级。总之，顺铂支气管动脉灌注化疗作为一种肺癌化疗方式，尤其是对鳞状细胞癌，是非常有用的，因为可以在不产生全身毒性的情况下给予更高的顺铂局部剂量。
