de Vries Ronald P, Grigoriev Igor V, Tsang Adrian
Fungal Physiology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.
United States Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Methods Mol Biol. 2018;1775:1-7. doi: 10.1007/978-1-4939-7804-5_1.
Genome sequences and postgenomic tools have had a major impact on fungal research. When the first fungal genome sequences became available it became clear how much more complex fungal biology was than had been previously assumed. Since then an increasing number of genomes have become available enabling detailed comparative studies, especially when combined with postgenomic tools such as transcriptomics and proteomics. This chapter provides an overview and current state of fungal genomics.
基因组序列和后基因组工具对真菌研究产生了重大影响。当第一批真菌基因组序列问世时,人们清楚地认识到真菌生物学比之前设想的要复杂得多。从那时起,越来越多的基因组可供使用,这使得详细的比较研究成为可能,尤其是当与转录组学和蛋白质组学等后基因组工具相结合时。本章概述了真菌基因组学及其当前状况。