Pirhadi Shiva, Mohammadi Neda, Mosavi Seyed Aliasghar, Daryabari Hashem, Aghamollaei Hossein, Jadidi Khosrow
Department of Biomedical Engineering, Tehran Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
BMC Ophthalmol. 2018 Jun 7;18(1):137. doi: 10.1186/s12886-018-0806-2.
This paper seeks to evaluate the depth and outcomes of MyoRing implantation using two mechanical dissection procedures including: PocketMaker microkeratome in opposition to the Melles hook method.
This retrospective study was carried out on 39 eyes of 38 keratoconus patients (28 male and 10 female) with the mean age of [Formula: see text] years and had undergone MyoRing implantation by the two mentioned methods. The MyoRing was inserted into the corneal pocket which was made manually in 18 eyes (Melles hook group) or with PocketMaker microkeratome in 21 eyes (PocketMaker group). The mean follow up time was [Formula: see text] months with pre-operative and post-operative ophthalmic examination including uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), keratometry readings and central corneal thickness measurement. AS-OCT (Casia, SS-1000, Tomey, Nagoya, Japan) imaging was used to measure MyoRing insertion depth, exactly.
Pre-operative and post-operative UCVA (LogMAR) mean change for the PocketMaker and Melles hook groups were recorded at 0.75 ± 0.32 and 0.78 ± 0.33, respectively. Similarly, BCVA (LogMAR) mean change were 0.27 ± 0.22 and 0.23 ± 0.22. Mean keratometry (Kmean) change were 6.06 ± 4.18 and 6.56 ± 3.55 respectively. UCVA change (P = 0.767), BCVA change (P = 0.77) and Kmean change (P = 0.693) showed that there was no statistically significant difference between both groups for any parameter. Depth measurements achieved from AS-OCT images showed that there was no statistically significant difference in pocket depth between two methods of MyoRing implantation (P = 0.413).
The results of Myoring implantation outcomes using mechanical dissection via PocketMaker microkeratome as against Melles hook are comparable.
本文旨在评估使用两种机械剖切方法植入MyoRing的深度及效果，这两种方法包括：与梅勒斯钩法相对的PocketMaker微型角膜刀。
对38例圆锥角膜患者（28例男性，10例女性）的39只眼进行了这项回顾性研究，患者平均年龄为[公式：见原文]岁，且均通过上述两种方法接受了MyoRing植入术。MyoRing被植入角膜袋中，其中18只眼的角膜袋是手动制作的（梅勒斯钩组），21只眼的角膜袋是用PocketMaker微型角膜刀制作的（PocketMaker组）。平均随访时间为[公式：见原文]个月，术前和术后均进行眼科检查，包括裸眼视力（UCVA）、最佳矫正视力（BCVA）、角膜曲率读数和中央角膜厚度测量。使用AS-OCT（Casia，SS-1000，日本名古屋多美公司）成像精确测量MyoRing的植入深度。
PocketMaker组和梅勒斯钩组术前和术后UCVA（LogMAR）的平均变化分别记录为0.75±0.32和0.78±0.33。同样，BCVA（LogMAR）的平均变化分别为0.27±0.22和0.23±0.22。平均角膜曲率（Kmean）变化分别为6.06±4.18和6.56±3.55。UCVA变化（P = 0.767）、BCVA变化（P = 0.77）和Kmean变化（P = 0.693）表明，两组在任何参数上均无统计学显著差异。从AS-OCT图像获得的深度测量结果表明，两种MyoRing植入方法在角膜袋深度上无统计学显著差异（P = 0.413）。
与梅勒斯钩法相比，使用PocketMaker微型角膜刀进行机械剖切植入MyoRing的效果相当。
