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全环板层角膜内植入术治疗重度圆锥角膜患者的高度近视

Full-ring Intrastromal Corneal Implantation for Correcting High Myopia in Patients with Severe Keratoconus.

作者信息

Jadidi Khosrow, Nejat Farhad, Mosavi Seyedali Asghar, Naderi Mostafa, Katiraee Ali, Janani Leila, Aghamollaei Hossein

机构信息

Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran, Iran; Bina Eye Hospital, Tehran, Iran.

Bina Eye Hospital, Tehran, Iran.

出版信息

Med Hypothesis Discov Innov Ophthalmol. 2016 Fall;5(3):89-95.

Abstract

The aim of this study was to evaluate the effect of the mechanical implantation of a MyoRing in patients with severe keratoconus and high myopia. The study involved 32 eyes of 32 patients (14 men and 18 women; mean age: 29.6 ± 6.7; age range: 20 - 44). The patients underwent MyoRing implantation with mechanical dissection using a Pocket Maker microkeratome, and outcomes were assessedat3 months after surgery. The main outcome measures were uncorrected and corrected distance visual acuity (UDVA and CDVA, both in Logarithm of the Minimum Angle of Resolution [logMAR] units), manifest refraction, and keratometry readings. There was a significant improvement in the UDVA, from 1.14 ± 0.32 to 0.35 ± 0.24 (P ˂ 0.001), and in the CDVA, from 0.47 ± 0.20 to 0.22 ± 0.15 (P ˂ 0.001). There was also a significant improvement in the spherical equivalent refractive error (-10.51 ± 2.81 D to -1.32 ± 2.29 D) (P ˂ 0.001). There was a significant decrease of manifest refraction in the mean sphere and cylinder of 7.70 and 2.6 D, respectively (P < 0.001). Furthermore, with regard to corneal topography, there was a significant reduction of 3.55 D (P ˂ 0.001) in the mean keratometry reading. The results show that the mechanical implantation of a MyoRing is effective for the correction of myopia in patients with keratoconus and high myopia.

摘要

本研究的目的是评估在重度圆锥角膜和高度近视患者中机械植入MyoRing的效果。该研究纳入了32例患者的32只眼(14例男性和18例女性;平均年龄:29.6±6.7岁;年龄范围:20 - 44岁)。患者使用Pocket Maker微型角膜刀进行机械分离后植入MyoRing,并在术后3个月评估结果。主要观察指标为未矫正和矫正远视力(UDVA和CDVA,均以最小分辨角对数[logMAR]单位表示)、显验光和角膜曲率读数。UDVA有显著改善,从1.14±0.32提高到0.35±0.24(P<0.001),CDVA从0.47±0.20提高到0.22±0.15(P<0.001)。等效球镜屈光不正也有显著改善(从-10.51±2.81 D降至-1.32±2.29 D)(P<0.001)。平均球镜和柱镜的显验光分别显著降低了7.70 D和2.6 D(P<0.001)。此外,关于角膜地形图,平均角膜曲率读数显著降低了3.55 D(P<0.001)。结果表明,机械植入MyoRing对圆锥角膜和高度近视患者的近视矫正有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4b/5347213/7be85064eba1/mehdiophth-5-089-g001.jpg

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