Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
Department of Emergency Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, United States.
Am J Emerg Med. 2018 Sep;36(9):1674-1679. doi: 10.1016/j.ajem.2018.05.078. Epub 2018 Jun 1.
In the United States, over 350,000 cardiac arrests occur outside of the hospital and 209,000 occur in the hospital. Shockable rhythms such as ventricular fibrillation (VF) have a survival rate of 20-30% outside of the hospital setting. Dual Sequential Defibrillation (DSD) has demonstrated success in terminating VF that is refractory to multiple attempts using a single defibrillator.
The PubMed, and MEDLINE databases were reviewed in February of 2018 and literature reviewed on dual sequential defibrillation. The terms "dual", "sequential", "double sequential", and "defibrillation" were added in the search builder. This search was limited to English-language articles. The results and their references were assessed for relevance to the topic and implications for dual sequential defibrillation in shockable cardiac arrest.
Included search terms yielded 23 articles. Studies occurred in the emergency department and prehospital setting. There are two retrospective cohort studies and the majority of published studies are case reports/series. Sample size per study varied from 1 to 279 encounters.
Studies have shown success in using DSD to treat refractory VF. However, further studies are necessary to assess the efficacy and safety of DSD compared to the standard of care treating refractory VF.
在美国,超过 35 万例心脏骤停发生在医院外,20.9 万例发生在医院内。在医院外环境中,除颤可恢复的节律(如室颤[VF])的存活率为 20-30%。双相顺序除颤(DSD)已被证明在终止对多次使用单个除颤器均无反应的 VF 方面取得了成功。
于 2018 年 2 月检索了 PubMed 和 MEDLINE 数据库,并对双相顺序除颤的文献进行了综述。在搜索构建器中添加了“双相”、“顺序”、“双相顺序”和“除颤”等术语。该搜索仅限于英文文章。评估了结果及其参考文献与主题的相关性以及在可除颤性心脏骤停中使用双相顺序除颤的意义。
包括的搜索词产生了 23 篇文章。研究发生在急诊科和院前环境中。有两项回顾性队列研究,大多数已发表的研究为病例报告/系列。每项研究的样本量从 1 到 279 次就诊不等。
研究表明,使用 DSD 治疗难治性 VF 取得了成功。然而,需要进一步的研究来评估 DSD 与治疗难治性 VF 的标准治疗相比的疗效和安全性。