Antimicrobial Resistance and Infectious Diseases Laboratory, School of Veterinary and Life Sciences, Murdoch University, Perth, Australia.
College of Veterinary Medicine, School of Veterinary and Life Sciences, Murdoch University, Perth, Australia.
Sci Rep. 2018 Jun 7;8(1):8725. doi: 10.1038/s41598-018-26920-5.
Camp dogs in indigenous communities in the Western Australian Kimberley Region, share the domestic environment with humans and have the potential to act as carriers of, and sentinels for, a wide range of zoonotic agents, including intestinal parasites and antimicrobial resistant bacteria. In this study, we investigated the carriage of extended-spectrum-cephalosporin-resistant (ESC-resistant) Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA) and species of hookworm and Giardia among camp dogs in remote Western Australian Aboriginal communities. A total of 141 canine faecal samples and 156 nasal swabs were collected from dogs in four communities of the Western Australian Kimberley region. Overall, ESC-resistant E. coli was detected in 16.7% of faecal samples and MRSA was isolated from 2.6% of nasal swabs. Of most significance was the presence of the community-associated Panton-Valentine leucocidin (PVL)-positive MRSA ST93 and ST5 clones and ESC-resistant E. coli ST38 and ST131. The most prevalent zoonotic intestinal parasite infection was Ancylostoma caninum (66%). The prevalence of Giardia was 12.1%, with the main genotypes of Giardia detected being dog specific assemblages C and D, which are unlikely to cause disease in humans.
在西澳大利亚金伯利地区的原住民社区中，营地犬与人类共同生活在家庭环境中，它们有可能成为多种人畜共患病原体的携带者和监测者，包括肠道寄生虫和抗微生物药物耐药细菌。在这项研究中，我们调查了偏远的西澳大利亚原住民社区中营地犬携带的超广谱头孢菌素耐药（ESC 耐药）大肠杆菌、耐甲氧西林金黄色葡萄球菌（MRSA）以及钩虫和贾第虫属的情况。从西澳大利亚金伯利地区的四个社区共采集了 141 份犬粪便样本和 156 份鼻拭子。总体而言，在 16.7%的粪便样本中检测到 ESC 耐药大肠杆菌，在 2.6%的鼻拭子中分离出 MRSA。最值得关注的是社区相关的泛耐药性溶葡萄球菌素（PVL）阳性 MRSA ST93 和 ST5 克隆以及 ESC 耐药大肠杆菌 ST38 和 ST131 的存在。最常见的人畜共患肠道寄生虫感染是犬钩虫（66%）。贾第虫的流行率为 12.1%，主要检测到的贾第虫基因型是犬特异性的 C 型和 D 型，不太可能导致人类患病。
