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近期淀粉纳米纤维的制备趋势:静电纺丝和非静电纺丝方法及其在生物技术中的应用。

Recent Trends in the Fabrication of Starch Nanofibers: Electrospinning and Non-electrospinning Routes and Their Applications in Biotechnology.

机构信息

Department of Nanotechnology, University of Kashmir, Srinagar, Jammu and Kashmir, 190006, India.

Center of Data Mining and Biomedical Informatics, Faculty of Medical technology, Mahidol University, Salaya, 73170, Thailand.

出版信息

Appl Biochem Biotechnol. 2019 Jan;187(1):47-74. doi: 10.1007/s12010-018-2797-0. Epub 2018 Jun 8.

Abstract

Electrospinning a versatile and the most preferred technique for the fabrication of nanofibers has revolutionized by opening unlimited avenues in biomedical fields. Presently, the simultaneous functionalization and/or post-modification of as-spun nanofibers with biomolecules has been explored, to serve the distinct goals in the aforementioned field. Starch is one of the most abundant biopolymers on the earth. Besides, being biocompatible and biodegradable in nature, it has unprecedented properties of gelatinization and retrogradation. Therefore, starch has been used in numerous ways for wide range of applications. Keeping these properties in consideration, the present article summarizes the recent expansion in the fabrication of the pristine/modified starch-based composite scaffolds by electrospinning along with their possible applications. Apart from electrospinning technique, this review will also provide the comprehensive information on various other techniques employed in the fabrication of the starch-based nanofibers. Furthermore, we conclude with the challenges to be overcome in the fabrication of nanofibers by the electrospinning technique and future prospects of starch-based fabricated scaffolds for exploration of its applications.

摘要

静电纺丝是一种通用且最受欢迎的纳米纤维制造技术,通过为生物医学领域开辟无限途径而发生了革命性变化。目前,已经探索了对纺丝纳米纤维进行生物分子的同时功能化和/或后修饰,以满足上述领域的不同目标。淀粉是地球上最丰富的生物聚合物之一。此外,由于其具有生物相容性和可生物降解性,因此具有独特的糊化和回生性质。因此,淀粉已被用于各种应用。考虑到这些特性,本文总结了通过静电纺丝制造原始/改性淀粉基复合支架的最新进展及其可能的应用。除了静电纺丝技术外,本综述还将提供有关用于制造淀粉基纳米纤维的各种其他技术的全面信息。此外,我们总结了通过静电纺丝技术制造纳米纤维所面临的挑战,并对淀粉基制造支架的未来前景进行了探索,以寻求其应用。

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