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Inputs from the A1 noradrenergic region to hypothalamic paraventricular neurons in the rat.

作者信息

Tanaka J, Kaba H, Saito H, Seto K

出版信息

Brain Res. 1985 Jun 3;335(2):368-71. doi: 10.1016/0006-8993(85)90496-2.

DOI:10.1016/0006-8993(85)90496-2
PMID:2988698
Abstract

Electrical stimulation of the rat A1 noradrenergic region produced excitation (77%) of the activity of putative vasopressin (VP)-secreting neurons in the paraventricular nucleus (PVN) and produced excitation (4%), inhibition (26%) and excitation-inhibition (11%) of the activity of PVN neurons that were not antidromically identified by neurohypophysial stimulation. The excitatory response of putative VP-secreting neurons was blocked by microiontophoretically applied phentolamine, an alpha-adrenoceptor antagonist, but not by timolol, a beta-adrenoceptor antagonist. The inhibitory response of unidentified PVN neurons, on the other hand, was blocked by timolol, but not by phentolamine.

摘要

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