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数字乳腺摄影术在乳腺癌检测中的诊断准确性

Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer.

作者信息

Zeeshan Muhammad, Salam Basit, Khalid Qazi Saad B, Alam Shahbaz, Sayani Raza

机构信息

Radiology, Royal Blackburn Hospital, Elht.

Department of Radiology, The Aga Khan University, Karachi, PAK.

出版信息

Cureus. 2018 Apr 8;10(4):e2448. doi: 10.7759/cureus.2448.

Abstract

Introduction Breast cancer has a high prevalence in the community and places very high demands on resources. Digital mammography provides a good quality image with reduced radiation dose and can detect breast carcinoma in its earlier stages, resulting in good prognosis and improved patient survival. Objective To calculate the diagnostic accuracy of digital mammography in the detection of breast cancer, using histopathology as a gold standard in women aged over 30 years, who are undergoing mammography for screening and diagnostic purposes. Materials and methods This was a cross-sectional analytical study, conducted in the department of radiology, for a total duration of 10 months. A total of 122 patients of age above 30 years, referred for digital mammography for the evaluation of different symptoms related to breast diseases, followed by biopsy/surgery and histopathology, were included in the study. Result Our data confirmed that digital mammography is a highly accurate tool for breast cancer detection having a sensitivity of 97%, a specificity of 64.5%, a positive predictive value of 89%, and a negative predictive value of 90.9%, with a diagnostic accuracy of 89.3%. Conclusion Considering our results, we recommend that digital mammography should replace screen-film mammography as a basic tool to detect breast cancer for both screening and diagnostic purposes.

摘要

引言

乳腺癌在社区中具有较高的患病率,对资源的需求也非常大。数字乳腺摄影可提供高质量图像,同时降低辐射剂量,并且能够在早期阶段检测出乳腺癌,从而带来良好的预后并提高患者生存率。

目的

以组织病理学作为金标准,计算数字乳腺摄影在30岁以上接受乳腺摄影筛查和诊断的女性中检测乳腺癌的诊断准确性。

材料和方法

这是一项在放射科进行的横断面分析研究,为期10个月。共有122名年龄在30岁以上的患者因评估与乳腺疾病相关的不同症状而接受数字乳腺摄影,随后进行活检/手术及组织病理学检查,纳入本研究。

结果

我们的数据证实,数字乳腺摄影是一种用于检测乳腺癌的高度准确的工具,其灵敏度为97%,特异度为64.5%,阳性预测值为89%,阴性预测值为90.9%,诊断准确性为89.3%。

结论

考虑到我们的结果,我们建议数字乳腺摄影应取代屏-片乳腺摄影,作为用于筛查和诊断目的检测乳腺癌的基本工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0977/5991925/6cfc4177005d/cureus-0010-00000002448-i01.jpg

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