Alshoabi Sultan Abdulwadoud, Alareqi Amal A, Gameraddin Moawia, Gareeballah Awadia, Alsultan Kamal D, Alzain Amel F
Department of Diagnostic Radiology Technology, College of Applied Medical Sciences, Taibah University, Al-Madinah Almunawwarah, Kingdom of Saudi Arabia.
Radiology Department, 21 September University of Medical and Applied Science, Sana'a, Republic of Yemen.
J Family Med Prim Care. 2025 Jan;14(1):341-347. doi: 10.4103/jfmpc.jfmpc_1225_24. Epub 2025 Jan 13.
Breast cancer (BC) is considered one of the most commonly diagnosed cancers. Early detection is critical for effective management. This study aims to assess the utility of ultrasonography (US) and mammography (MG) in detecting BC features.
This retrospective cross-sectional study involved the electronic records of 263 female patients diagnosed with BC. The mean age was 45.71 ± 12.25 years (17-90 years). A cross-tabulation test was performed to correlate the presence of each malignant feature (Yes/No) on both US and MG and the final ultrasonography diagnosis (benign/malignant). The compatibility between the presence of each feature on both imaging techniques was measured by the percentage of agreement in reporting the feature that was reported as Kappa. The sensitivity and specificity for each feature were calculated, and the receiver operating characteristic curve was used to measure the area under the curve for each feature on both modalities.
The strong compatibility between the two techniques was 87.1%, 94.29%, 66.92%, 79.85%, 77.56%, 77.18, and 79.84% for irregular shape, uncircumscribed, spiculated margins, tissue distortion, nipple retraction, skin thickening, and the presence of lymphadenopathy, respectively ( < 0.001). Boxplots show that the sensitivity of the US ranged from 37% to 95%, and the specificity ranged from 27% to 91%. However, MG's sensitivity ranged from 44% to 93%, and the specificity ranged from 36% to 73%.
US and MG images show similar morphological changes, enhancing diagnostic accuracy in breast lesions. US characterizes echogenicity, provides real-time imaging, and uses color and pulsed Doppler techniques for vascularity and lymphadenopathy detection, while MG is better for identifying different calcification types.
乳腺癌（BC）被认为是最常被诊断出的癌症之一。早期检测对于有效治疗至关重要。本研究旨在评估超声检查（US）和乳腺X线摄影（MG）在检测乳腺癌特征方面的效用。
这项回顾性横断面研究涉及263例被诊断为乳腺癌的女性患者的电子记录。平均年龄为45.71±12.25岁（17 - 90岁）。进行交叉制表测试，以关联US和MG上每个恶性特征（是/否）的存在情况与最终超声诊断结果（良性/恶性）。通过报告为Kappa的特征一致性百分比来衡量两种成像技术上每个特征存在情况之间的兼容性。计算每个特征的敏感性和特异性，并使用受试者操作特征曲线来测量两种模式下每个特征的曲线下面积。
两种技术在不规则形状、边界不清、边缘毛刺状、组织变形、乳头回缩、皮肤增厚和存在淋巴结病方面的强兼容性分别为87.1%、94.29%、66.92%、79.85%、77.56%、77.18%和79.84%（P<0.001）。箱线图显示，US的敏感性范围为37%至95%，特异性范围为27%至91%。然而，MG的敏感性范围为44%至93%，特异性范围为36%至73%。
US和MG图像显示出相似的形态学变化，提高了乳腺病变的诊断准确性。US可表征回声性，提供实时成像，并使用彩色和脉冲多普勒技术检测血管和淋巴结病，而MG更擅长识别不同类型的钙化。
