Kankaya Burak, Buyukasik Suleyman, Altundal Yusuf Emre, Topcu Feyza Sonmez, Rahmanbakhsh Paria, Etemad Ayden, Kapan Selin, Alis Halil
Department of General Surgery, Faculty of Medicine, Istanbul Aydin University, Istanbul, Turkey.
Department of Radiology, Faculty of Medicine, Istanbul Aydin University, Istanbul, Turkey.
Breast Cancer (Dove Med Press). 2025 Feb 6;17:115-122. doi: 10.2147/BCTT.S481201. eCollection 2025.
Our study has three main aims: 1) to assess the distribution of Breast Imaging Reporting and Data System (BI-RADS) classifications in a cohort of Turkish women undergoing screening mammography, 2) to analyze the frequency and non-completion rates of recommended follow-up ultrasound (US) examinations, and 3) to examine the outcomes of completed follow-up US examinations. Our goal was to evaluate potential gaps in the current breast cancer screening process by analyzing BI-RADS classifications, follow-up completion rates, and outcomes of completed ultrasound examinations.
This retrospective study analyzed 1761 Turkish women who underwent screening mammography from 2020-2022 at the Istanbul Aydin University General Surgery Clinic, Istanbul, Turkey. We assessed the distribution of BI-RADS classifications, analyzed the frequency and non-completion rates of recommended follow-up US, and examined the outcomes of completed follow-up US examinations. Chi-square tests of independence and Spearman's rank correlation test were used to analyze the data.
Our study revealed three key findings: 1) Over half of mammograms (55.9%) were classified as BI-RADS 0, requiring further imaging. 2) Nearly one-third of patients who recommended US examinations (31.91%) did not complete recommended follow-up ultrasound appointments. 3) Among those who completed follow-up ultrasonography, almost one-third (29.7%) were reclassified as BI-RADS 3 or higher. Notably, 2.3% (n=18) were classified as BI-RADS 4 or 5, suggesting findings suspicious for malignancy.
Our findings highlight the crucial role of follow-up US in breast cancer screening. The high rate of initial BI-RADS 0 classifications using mammography, coupled with the significant non-completion rate for follow-up US examinations, particularly among older age groups, highlights potential gaps in the current screening process.
我们的研究有三个主要目标:1)评估接受乳腺钼靶筛查的土耳其女性队列中乳腺影像报告和数据系统(BI-RADS)分类的分布情况;2)分析推荐的后续超声(US)检查的频率和未完成率;3)检查已完成的后续超声检查的结果。我们的目标是通过分析BI-RADS分类、后续检查完成率和已完成超声检查的结果,评估当前乳腺癌筛查过程中的潜在差距。
这项回顾性研究分析了2020年至2022年在土耳其伊斯坦布尔艾登大学普通外科诊所接受乳腺钼靶筛查的1761名土耳其女性。我们评估了BI-RADS分类的分布情况,分析了推荐的后续超声检查的频率和未完成率,并检查了已完成的后续超声检查的结果。使用独立性卡方检验和斯皮尔曼等级相关检验来分析数据。
我们的研究揭示了三个关键发现:1)超过一半的乳腺钼靶检查(55.9%)被分类为BI-RADS 0,需要进一步成像。2)近三分之一推荐进行超声检查的患者(占31.91%)未完成推荐的后续超声检查预约。3)在完成后续超声检查的患者中,近三分之一(29.7%)被重新分类为BI-RADS 3或更高。值得注意的是,2.3%(n = 18)被分类为BI-RADS 4或5,提示有恶性可疑表现。
我们的研究结果凸显了后续超声检查在乳腺癌筛查中的关键作用。乳腺钼靶检查初始BI-RADS 0分类的高比例,加上后续超声检查的显著未完成率,尤其是在老年人群中,凸显了当前筛查过程中的潜在差距。