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功能性毛细管管内润湿性改变用于可视化即时护理点检测的定量分析。

Wettability alteration in a functional capillary tube for visual quantitative point of care testing.

机构信息

Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, China.

出版信息

Analyst. 2018 Jul 7;143(13):3001-3005. doi: 10.1039/c8an00735g. Epub 2018 Jun 11.

DOI:10.1039/c8an00735g
PMID:29888353
Abstract

Capillarity is an extremely common physical-chemical phenomenon related to wettability in nature, which has wide theoretical and practical interest. Herein, we reported a facile sensing device based on capillary force change in a vertical capillary tube. In this height-based capillary sensor (HCS), the inner surface of the capillary tube was modified with a layer of molecules with wetting responsibility based on the well-known simple surface chemistry. With targets in different concentrations, the wettability of the surface modified with responsive molecules would produce different changes. The responsive surfaces would change the capillary force of the vertical capillary tube, and result in different column heights. Like a thermometer, H and phenol have been quantified visually based on the height of the liquid inside the capillary tube.

摘要

毛细现象是一种与自然界润湿性密切相关的极其常见的物理化学现象,具有广泛的理论和实际意义。在此,我们报道了一种基于垂直毛细管所受毛细作用力变化的简易传感装置。在这种基于高度的毛细传感器(HCS)中,毛细管的内表面用一层基于众所周知的简单表面化学的具有润湿性响应的分子进行了修饰。对于不同浓度的目标物,用响应分子修饰后的表面的润湿性会产生不同的变化。响应表面会改变垂直毛细管的毛细作用力,从而导致不同的柱高。与温度计一样,H 和苯酚可通过毛细管所内液体的高度进行直观定量。

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