Emelifeonwu John Amaechi, Shetty Jay, Kaliaperumal Chandrasekaran, Gallo Pasquale, Sokol Drahoslav, Soleiman Hamza, Kandasamy Jegajothy
1 Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.
2 Department of Clinical Neurosciences, Royal Hospital for Sick Children, Edinburgh, UK.
J Child Neurol. 2018 Sep;33(10):675-684. doi: 10.1177/0883073818777673. Epub 2018 Jun 11.
Acute cerebellar ataxia is the most common cause of acute ataxia in children and it usually runs a self-limiting and ultimately benign clinical course. A small proportion of children have evidence of inflammatory swelling in the cerebellum. Many of these children suffer more severe and potentially life-threatening forms of cerebellar ataxia and may need more intensive treatments including urgent neurosurgical treatments. This more severe form of acute cerebellar ataxia is often termed acute cerebellitis. Many children with acute cerebellitis have long-term neurological sequela and evidence of structural cerebellar changes on follow-up imaging. Several patterns of cerebellar inflammation have been described. The authors describe the variabilities in the clinical and radiological patterns of disease in the cases that have been described in the literature.
急性小脑性共济失调是儿童急性共济失调最常见的病因，通常呈自限性且最终临床病程良性。一小部分儿童有小脑炎症性肿胀的证据。这些儿童中有许多患有更严重且可能危及生命的小脑性共济失调形式，可能需要更强化的治疗，包括紧急神经外科治疗。这种更严重形式的急性小脑性共济失调通常被称为急性小脑炎。许多急性小脑炎患儿有长期神经后遗症，随访影像学检查有小脑结构改变的证据。已经描述了几种小脑炎症模式。作者描述了文献中所报道病例的疾病临床和放射学模式的变异性。
