急性重度溃疡性结肠炎的当代医学管理
Contemporary Medical Management of Acute Severe Ulcerative Colitis.
机构信息
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
出版信息
Inflamm Bowel Dis. 2019 Jan 1;25(1):56-66. doi: 10.1093/ibd/izy208.
Abstract
Acute severe ulcerative colitis is a medical emergency that requires prompt recognition, evaluation, and intervention. Patients require hospital admission with laboratory, radiographic, and endoscopic evaluation with initiation of corticosteroid treatment. Despite early intervention, many patients require salvage medical therapy, with some progressing to colectomy. Here we review important concepts and recent advances in the evaluation and medical management of adult and pediatric patients with acute severe ulcerative colitis.
摘要
急性重度溃疡性结肠炎是一种医学急症，需要及时识别、评估和干预。患者需要住院，进行实验室、影像学和内镜评估，并开始皮质类固醇治疗。尽管早期干预，许多患者仍需要挽救性药物治疗，部分患者进展为结肠切除术。本文复习了成人和儿童急性重度溃疡性结肠炎患者的评估和药物治疗的重要概念和最新进展。
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