Zvenigorodskaya L A, Petrakov A V, Nilova T V, Varvanina G G, Lychkova A E
Eksp Klin Gastroenterol. 2016(11):31-34.
Bile acids regulate glucose and lipid metabolism. Aim -determination of total serum bile acids in patients with NAFLD and in combination with type 2 diabetes. To determine the inflammatory markers (nitric oxide, endotoxin, phospholipase A2, malondialdehyde) effects role for the synthesis and transport of bile acids. NAFLD patients with type 2 diabetes observed decrease in synthesis and disruption of transport of bile acids, which is associated with the cell membrane damage by inhibition of enzyme systems, and inflammation.
胆汁酸调节葡萄糖和脂质代谢。目的——测定非酒精性脂肪性肝病（NAFLD）患者以及合并2型糖尿病患者的血清总胆汁酸。确定炎症标志物（一氧化氮、内毒素、磷脂酶A2、丙二醛）对胆汁酸合成和转运的作用。观察到合并2型糖尿病的NAFLD患者胆汁酸合成减少及转运障碍，这与酶系统受抑制导致的细胞膜损伤及炎症有关。
