Lu Y L, Sobis H, van Hove L, Vandeputte M
Eur J Cancer Clin Oncol. 1985 May;21(5):631-6. doi: 10.1016/0277-5379(85)90092-6.
The development of hemangiomas in grafts of visceral yolk sac and embryos after in vitro infection with polyoma virus is described. These hemangiomas were shown to be positive for the polyoma tumor-specific transplantation antigen(s) and to develop as well in recipient virgin as in pregnant rats. In grafts of fetal skin or gut infected with polyoma virus neoplastic transformation was never observed.
本文描述了用多瘤病毒体外感染后，内脏卵黄囊和胚胎移植物中血管瘤的发展情况。这些血管瘤被证明对多瘤肿瘤特异性移植抗原呈阳性反应，并且在未孕大鼠和孕鼠的受体中均能发展。在用多瘤病毒感染的胎儿皮肤或肠道移植物中，从未观察到肿瘤转化现象。
