Kondo T, Nonaka H, Miyamoto N, Yoshida R, Matsue Y, Ohguchi Y, Inouye H, Komoda H, Hinuma Y, Hanaoka M
Int J Cancer. 1985 Jun 15;35(6):749-51. doi: 10.1002/ijc.2910350609.
The yearly incidence of ATLL in the Uwajima district is 6.6 patients per 100,000 inhabitants aged over 40. The yearly morbidity rate from ATLL of persons in this district who are positive for HTLV-antibody and older than 40 is 1 patient per 1,631. Familial occurrence was observed in 9/38 families available for pedigree analyses. Even in the endemic area, the existence of positive HTLV antibody is remarkably high in ATLL families, suggesting that HTLV has been transmitted from generation to generation mainly within these particular families.
宇和岛地区成人T细胞白血病/淋巴瘤（ATLL）的年发病率为每10万40岁以上居民中有6.6例患者。该地区HTLV抗体呈阳性且年龄超过40岁的人群中，ATLL的年发病率为每1631人中有1例患者。在可供系谱分析的38个家族中，有9个家族观察到家族聚集现象。即使在流行地区，ATLL家族中HTLV抗体阳性的比例也非常高，这表明HTLV主要在这些特定家族中代代相传。
